Yamawake Ginroku, Yoshida Seiji, Tanaka Hidetaka, Kurooka Yusuke, Kubo Atsuko, Ota Yoshitaka, Mizutani Midori, Ashida Akira
Department of Pediatrics, Osaka Medical and Pharmaceutical University Hospital, Takatsuki, Japan.
Tanaka OD Hypotension Clinic, Osaka, Japan.
Front Pediatr. 2025 May 22;13:1573091. doi: 10.3389/fped.2025.1573091. eCollection 2025.
Abdominal compression is an effective nonpharmacological treatment for orthostatic intolerance. Although the efficacy of abdominal compression bands has been studied in adults, studies involving children are limited. This study investigates the efficacy of abdominal compression bands in children diagnosed with postural tachycardia syndrome (POTS), using a larger cohort and incorporating autonomic nervous function assessment via frequency analysis.
A crossover study was conducted with 23 patients with POTS (mean age 13.4 ± 0.8 years), with and without abdominal compression bands (20 mmHg). Standing symptoms, hemodynamics (blood pressure, heart rate [HR], cardiac index [CI], stroke volume [SV], and total peripheral resistance [TPR]), and cardiovascular autonomic function were assessed by spectrum analysis during standing tests. These variables were compared with and without bands.
When standing with the abdominal compression band, subjective symptoms improved, increases in heart rate (HR) and decreases in stroke volume (SV) were suppressed, blood pressure was maintained, and cardiac parasympathetic function was improved. By contrast, in the supine position, patients showed an increased HR, decreased CI, increased TPR, lower cardiac parasympathetic function, and higher cardiac sympathetic function.
Abdominal compression bands may relieve symptoms while standing and improve hemodynamic and autonomic nervous functions in children with POTS.
腹部加压是治疗体位性不耐受的一种有效的非药物疗法。虽然腹部加压带的疗效已在成人中进行了研究，但涉及儿童的研究有限。本研究采用更大的队列并通过频率分析纳入自主神经功能评估，探讨腹部加压带对诊断为体位性心动过速综合征（POTS）儿童的疗效。
对23例POTS患者（平均年龄13.4±0.8岁）进行交叉研究，分别在使用和不使用腹部加压带（20 mmHg）的情况下，在站立试验期间通过频谱分析评估站立症状、血流动力学（血压、心率[HR]、心脏指数[CI]、每搏输出量[SV]和总外周阻力[TPR]）以及心血管自主神经功能。对使用和不使用加压带时的这些变量进行比较。
佩戴腹部加压带站立时，主观症状改善，心率（HR）增加和每搏输出量（SV）减少受到抑制，血压得以维持，心脏副交感神经功能得到改善。相比之下，在仰卧位时，患者心率增加、CI降低、TPR增加、心脏副交感神经功能降低且心脏交感神经功能增强。
腹部加压带可能会缓解POTS患儿站立时的症状，并改善其血流动力学和自主神经功能。
