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肾移植后肝脏的病例研究:采用定制的手术及术后方法治疗多囊性疾病

A Case Study of Liver After Kidney Transplantation: Addressing Polycystic Diseases With Tailored Surgical and Postoperative Approaches.

作者信息

Sun Chengjun, Du Yang, Han Ming, Shi Shaojun, Wu Linwei

机构信息

Department of Organ Transplantation, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China.

出版信息

Clin Case Rep. 2025 Jun 4;13(6):e70484. doi: 10.1002/ccr3.70484. eCollection 2025 Jun.

Abstract

Polycystic liver disease is a hereditary disease, which is characterized by the presence of multiple cysts within the liver. In this case, we report a patient with multiple cysts in the kidneys and liver, who underwent kidney transplantation in 2019 and then liver transplantation 4 years later. The complexities of performing liver transplantation in a patient with a prior kidney transplant were significant, particularly due to the enlarged liver obscuring critical vascular structures and necessitating careful intraoperative strategies, such as the side-to-side anastomosis or piggyback techniques to ensure venous return and protect the renal graft. One year post-transplant, the patient exhibited stable liver and kidney functions, demonstrating the feasibility of liver transplantation after kidney transplantation from different donor grafts. The surgical technique and perioperative management require careful consideration.

摘要

多囊肝病是一种遗传性疾病,其特征是肝脏内存在多个囊肿。在此,我们报告一例肾脏和肝脏均有多个囊肿的患者,该患者于2019年接受了肾移植,4年后又接受了肝移植。在先前接受过肾移植的患者中进行肝移植的复杂性很高,尤其是因为肝脏肿大模糊了关键血管结构,需要精心的术中策略,如侧侧吻合或背驮式技术,以确保静脉回流并保护肾移植。移植后一年,患者的肝脏和肾脏功能稳定,证明了从不同供体移植物进行肾移植后再进行肝移植的可行性。手术技术和围手术期管理需要仔细考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c19d/12137191/d6001e243271/CCR3-13-e70484-g001.jpg

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