Ryo Hiroaki, Nakaminato Shuichiro, Yamaya Naohiro, Jeong Changwon, Obi Eiki
Department of Radiology, Kameda Medical Center, Kamogawa, JPN.
Cureus. 2025 May 6;17(5):e83549. doi: 10.7759/cureus.83549. eCollection 2025 May.
Hepatic encephalopathy is a serious complication of liver cirrhosis often associated with portosystemic shunts (PSSs), which may be refractory to medical management. We present the case of a 58-year-old man with liver cirrhosis who developed recurrent hepatic encephalopathy associated with mesorenal and paraumbilical PSSs. Despite medical therapy, his symptoms recurred, necessitating interventional treatment. The first session consisted of partial splenic embolization and balloon-occluded retrograde transvenous obliteration (BRTO) of the mesorenal shunt via the transjugular route, resulting in transient improvement. Due to recurrence of encephalopathy, a second BRTO was performed via percutaneous trans-paraumbilical venous access under ultrasound guidance, allowing for stable catheterization and successful embolization with detachable coils, and partial splenic embolization was also performed during the second session to further control portal pressure. Following the procedures, the patient achieved sustained clinical and biochemical improvement, with no recurrence of encephalopathy during seven months of follow-up. This case highlights the safety and utility of the trans-paraumbilical venous approach as an alternative access route for BRTO in patients with complex PSSs.
肝性脑病是肝硬化的一种严重并发症,常与门体分流(PSS)相关,可能对药物治疗无效。我们报告一例58岁肝硬化男性患者,其出现与脾肾分流和脐旁分流相关的复发性肝性脑病。尽管进行了药物治疗,但其症状仍复发,需要进行介入治疗。第一次治疗包括经颈静脉途径对脾肾分流进行部分脾栓塞和球囊闭塞逆行经静脉栓塞术(BRTO),结果病情暂时改善。由于脑病复发,在超声引导下经皮经脐静脉途径进行了第二次BRTO,实现了稳定置管并成功用可脱卸弹簧圈栓塞,第二次治疗期间还进行了部分脾栓塞以进一步控制门静脉压力。治疗后,患者临床和生化指标持续改善,随访7个月期间肝性脑病未复发。该病例突出了经脐静脉途径作为复杂PSS患者BRTO替代入路的安全性和实用性。