Prozesky L, Du Plessis J L
Onderstepoort J Vet Res. 1985 Jun;52(2):71-9.
Gross and microscopical lesions in mice intravenously infected with the Welgevonden strain of Cowdria ruminantium closely resembled the lesions described in cattle, sheep and goats. A high concentration of organisms was present in alveolar endothelial cells. Cytopathic changes in parasitized and non-parasitized endothelial cells and the morphology of the organisms are described and compared with the Ball3 strain of C. ruminantium. Possible mechanisms in the development of the lung oedema are considered and the role of mice as animal model is discussed.
静脉感染反刍兽考德里氏体韦尔格芬登菌株的小鼠的大体和微观病变与牛、羊和山羊中描述的病变非常相似。肺泡内皮细胞中存在高浓度的病原体。描述了被寄生和未被寄生的内皮细胞中的细胞病变变化以及病原体的形态，并与反刍兽考德里氏体的Ball3菌株进行了比较。考虑了肺水肿发展的可能机制，并讨论了小鼠作为动物模型的作用。
