Prozesky L
Section of Pathology, Veterinary Research Institute, Onderstepoort, South Africa.
Onderstepoort J Vet Res. 1987 Sep;54(3):281-6.
The pathological changes in cattle, sheep, goats, mice and various game species infected with Cowdria ruminantium are summarized. Macroscopical lesions in most animals include effusion of body cavities, oedema of the lungs and lymph nodes and splenomegaly. Apart from the presence of heartwater organisms in most organs the histopathological lesions are not striking. The ultrastructural lesions in the lungs of sheep and goats infected with the Ba11 3 strain of heartwater, and mice infected with the Welgevonden strain, are discussed. Damage to capillary endothelial cells of the alveoli is limited and the mild cytopathic changes in parasitized cells indicate that the damage caused by the organisms is most probably not responsible for the increased vascular permeability associated with the disease. Pathological changes in domestic ruminants and game animals are briefly compared.
总结了感染反刍兽立克次氏体的牛、羊、山羊、小鼠及各种猎物的病理变化。大多数动物的宏观病变包括体腔积液、肺和淋巴结水肿以及脾肿大。除了在大多数器官中存在心水菌外，组织病理学病变并不明显。讨论了感染心水菌Ba11 3株的绵羊和山羊以及感染韦尔格冯登株的小鼠肺部的超微结构病变。肺泡毛细血管内皮细胞的损伤有限，寄生细胞中的轻微细胞病变变化表明，该菌所造成的损伤很可能与该病相关的血管通透性增加无关。简要比较了家养反刍动物和猎物的病理变化。
