Frumence Etienne, Piorkowski Géraldine, Traversier Nicolas, Amaral Rayane, Vincent Muriel, Mercier Ambroise, Ayhan Nazli, Souply Laurent, Pezzi Laura, Lier Clément, Grard Gilda, Durand Guillaume André, Deparis Xavier, Thouillot Fabian, de Lamballerie Xavier, Klitting Raphaelle, Jaffar-Bandjee Marie-Christine
Associated National Reference Center for Arboviruses, CHU-Réunion, Saint-Denis, Réunion, France.
Laboratoire de microbiologie, CHU de la Réunion-Site Nord, Saint-Denis, Réunion, France.
Euro Surveill. 2025 Jun;30(22). doi: 10.2807/1560-7917.ES.2025.30.22.2500344.
Chikungunya virus re-emerged on Réunion Island in August 2024, 18 years after a first major outbreak. Analysis of 173 genomes from the current epidemic reveals a monophyletic clade with mutations linked to adaptation to mosquitoes, including E1-A226V. Bayesian inference suggests only brief cryptic circulation before detection. The same lineage was also detected on Mayotte Island in March 2025. Continued spread and confirmed travel-related cases in mainland France and globally highlight the risk of wider regional and international dissemination.
基孔肯雅病毒在首次大规模爆发18年后，于2024年8月在留尼汪岛再次出现。对此次疫情中173个基因组的分析揭示了一个单系分支，其携带的突变与适应蚊子有关，包括E1-A226V。贝叶斯推断表明，在检测到之前仅存在短暂的隐匿传播。2025年3月在马约特岛也检测到了相同的谱系。在法国大陆和全球范围内持续传播以及确诊的与旅行相关的病例凸显了更广泛的区域和国际传播风险。
