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左主干经皮冠状动脉介入治疗中的支架置入策略与影像应用:来自一项15年注册研究的见解

Stenting strategy and imaging use in left main percutaneous coronary intervention: insights from a 15-year registry.

作者信息

Andreka Judit, Malik Fazila-Tun-Nesa, Khandaker Mariam, Uddin Kalim, Kayum Abdul, Maaroufi Anass, Prunea Dan, Ruzsa Zoltan, Toth Gabor G

机构信息

Department of Cardiology, University Heart Center Graz, Medical University of Graz, Graz, Austria.

Department of Cardiology, University of Szeged, Szeged, Hungary.

出版信息

Future Cardiol. 2025 Jul;21(9):693-700. doi: 10.1080/14796678.2025.2511416. Epub 2025 Jun 6.

DOI:10.1080/14796678.2025.2511416
PMID:40476636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12258215/
Abstract

BACKGROUND

Left main (LM) percutaneous coronary intervention (PCI) remains a major interventional challenge, with outcomes influenced by various patient- and procedure-related factors.

OBJECTIVES

To analyze procedural characteristics and outcomes of patients who underwent LM PCI over a 15-year period in a single center.

METHODS

We retrospectively analyzed data from all consecutive patients who underwent LM PCI between 2006 and 2022. Procedural details, with a focus on stenting technique, were collected. Primary outcome was all-cause mortality at 1 year.

RESULTS

In total 3494 patients were included. The majority (67%) presented with chronic coronary syndrome. Seventy-seven percent of all patients (n = 2690) underwent PCI by single stent (SS) strategy and 23% (n = 804) by double stent (DS) strategy. One-year mortality was significantly lower in SS cases compared to DS (3.5% vs. 5.1%, HR 0.64, 95% CI 0.43-0.96). Intravascular imaging was used in 17% of the cases but showed no significant difference in one-year mortality compared to angio-guided PCI (4.8% vs. 3.7%; HR 1.11, 95% CI 0.71-1.73).

CONCLUSIONS

In real-world LM PCI practice, patients for whom a provisional single-stent strategy was feasible had better outcomes than those requiring a double-stent approach.

摘要

背景

左主干(LM)经皮冠状动脉介入治疗(PCI)仍然是一项重大的介入挑战,其结果受多种患者和手术相关因素影响。

目的

分析在单一中心15年间接受左主干PCI患者的手术特征和结果。

方法

我们回顾性分析了2006年至2022年间所有连续接受左主干PCI患者的数据。收集了手术细节,重点是支架置入技术。主要结局是1年时的全因死亡率。

结果

共纳入3494例患者。大多数(67%)表现为慢性冠状动脉综合征。所有患者中77%(n = 2690)采用单支架(SS)策略进行PCI,23%(n = 804)采用双支架(DS)策略。与双支架策略相比,单支架策略组的1年死亡率显著更低(3.5%对5.1%,HR 0.64,95%CI 0.43 - 0.96)。17%的病例使用了血管内成像,但与血管造影引导的PCI相比,1年死亡率无显著差异(4.8%对3.7%;HR 1.11,95%CI 0.71 - 1.73)。

结论

在现实世界的左主干PCI实践中,可行临时单支架策略的患者比需要双支架方法的患者结局更好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7df/12258215/dfd35153cfff/IFCA_A_2511416_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7df/12258215/c97ff575a33b/IFCA_A_2511416_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7df/12258215/15dc270c6221/IFCA_A_2511416_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7df/12258215/54cedf135bd3/IFCA_A_2511416_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7df/12258215/dfd35153cfff/IFCA_A_2511416_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7df/12258215/c97ff575a33b/IFCA_A_2511416_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7df/12258215/15dc270c6221/IFCA_A_2511416_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7df/12258215/54cedf135bd3/IFCA_A_2511416_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7df/12258215/dfd35153cfff/IFCA_A_2511416_F0004_OC.jpg

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本文引用的文献

1
2024 ESC Guidelines for the management of chronic coronary syndromes.2024年欧洲心脏病学会慢性冠状动脉综合征管理指南
Eur Heart J. 2024 Sep 29;45(36):3415-3537. doi: 10.1093/eurheartj/ehae177.
2
Clinical Benefit of Intravascular Imaging Compared With Conventional Angiography in Left Main Coronary Artery Intervention.血管内影像学与常规血管造影在左主干冠状动脉介入治疗中的临床获益比较。
Circ Cardiovasc Interv. 2023 Dec;16(12):e013359. doi: 10.1161/CIRCINTERVENTIONS.123.013359. Epub 2023 Nov 29.
3
2022 Joint ESC/EACTS review of the 2018 guideline recommendations on the revascularization of left main coronary artery disease in patients at low surgical risk and anatomy suitable for PCI or CABG.
2022 年 ESC/EACTS 联合对 2018 年指南建议的回顾:低手术风险且适合 PCI 或 CABG 解剖结构的左主干冠状动脉疾病患者的血运重建。
Eur Heart J. 2023 Nov 1;44(41):4310-4320. doi: 10.1093/eurheartj/ehad476.
4
Intravascular Imaging-Guided or Angiography-Guided Complex PCI.血管内影像学指导或血管造影指导下的复杂 PCI。
N Engl J Med. 2023 May 4;388(18):1668-1679. doi: 10.1056/NEJMoa2216607. Epub 2023 Mar 5.
5
2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2021年美国心脏病学会/美国心脏协会/心血管造影和介入学会冠状动脉血运重建指南:美国心脏病学会/美国心脏协会临床实践指南联合委员会报告
Circulation. 2022 Jan 18;145(3):e18-e114. doi: 10.1161/CIR.0000000000001038. Epub 2021 Dec 9.
6
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Lancet. 2021 Dec 18;398(10318):2247-2257. doi: 10.1016/S0140-6736(21)02334-5. Epub 2021 Nov 15.
7
The European bifurcation club Left Main Coronary Stent study: a randomized comparison of stepwise provisional vs. systematic dual stenting strategies (EBC MAIN).欧洲分叉俱乐部左主干冠状动脉支架研究:分步临时与系统双支架策略的随机比较(EBC MAIN)。
Eur Heart J. 2021 Oct 1;42(37):3829-3839. doi: 10.1093/eurheartj/ehab283.
8
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EuroIntervention. 2021 Jun 11;17(2):e124-e131. doi: 10.4244/EIJ-D-20-01121.
9
Multicentre, randomized comparison of two-stent and provisional stenting techniques in patients with complex coronary bifurcation lesions: the DEFINITION II trial.多中心、随机对照研究:复杂冠状动脉分叉病变患者中双支架技术与临时支架置入技术的比较——DEFINITION II试验
Eur Heart J. 2020 Jul 14;41(27):2523-2536. doi: 10.1093/eurheartj/ehaa543.
10
Mapping interventional cardiology in Europe: the European Association of Percutaneous Cardiovascular Interventions (EAPCI) Atlas Project.欧洲介入心脏病学图谱:欧洲经皮心血管介入协会(EAPCI)图谱项目
Eur Heart J. 2020 Jul 14;41(27):2579-2588. doi: 10.1093/eurheartj/ehaa475.