Andreka Judit, Malik Fazila-Tun-Nesa, Khandaker Mariam, Uddin Kalim, Kayum Abdul, Maaroufi Anass, Prunea Dan, Ruzsa Zoltan, Toth Gabor G
Department of Cardiology, University Heart Center Graz, Medical University of Graz, Graz, Austria.
Department of Cardiology, University of Szeged, Szeged, Hungary.
Future Cardiol. 2025 Jul;21(9):693-700. doi: 10.1080/14796678.2025.2511416. Epub 2025 Jun 6.
Left main (LM) percutaneous coronary intervention (PCI) remains a major interventional challenge, with outcomes influenced by various patient- and procedure-related factors.
To analyze procedural characteristics and outcomes of patients who underwent LM PCI over a 15-year period in a single center.
We retrospectively analyzed data from all consecutive patients who underwent LM PCI between 2006 and 2022. Procedural details, with a focus on stenting technique, were collected. Primary outcome was all-cause mortality at 1 year.
In total 3494 patients were included. The majority (67%) presented with chronic coronary syndrome. Seventy-seven percent of all patients (n = 2690) underwent PCI by single stent (SS) strategy and 23% (n = 804) by double stent (DS) strategy. One-year mortality was significantly lower in SS cases compared to DS (3.5% vs. 5.1%, HR 0.64, 95% CI 0.43-0.96). Intravascular imaging was used in 17% of the cases but showed no significant difference in one-year mortality compared to angio-guided PCI (4.8% vs. 3.7%; HR 1.11, 95% CI 0.71-1.73).
In real-world LM PCI practice, patients for whom a provisional single-stent strategy was feasible had better outcomes than those requiring a double-stent approach.
左主干(LM)经皮冠状动脉介入治疗(PCI)仍然是一项重大的介入挑战,其结果受多种患者和手术相关因素影响。
分析在单一中心15年间接受左主干PCI患者的手术特征和结果。
我们回顾性分析了2006年至2022年间所有连续接受左主干PCI患者的数据。收集了手术细节,重点是支架置入技术。主要结局是1年时的全因死亡率。
共纳入3494例患者。大多数(67%)表现为慢性冠状动脉综合征。所有患者中77%(n = 2690)采用单支架(SS)策略进行PCI,23%(n = 804)采用双支架(DS)策略。与双支架策略相比,单支架策略组的1年死亡率显著更低(3.5%对5.1%,HR 0.64,95%CI 0.43 - 0.96)。17%的病例使用了血管内成像,但与血管造影引导的PCI相比,1年死亡率无显著差异(4.8%对3.7%;HR 1.11,95%CI 0.71 - 1.73)。
在现实世界的左主干PCI实践中,可行临时单支架策略的患者比需要双支架方法的患者结局更好。