华法林与草药“卡达”相互作用的病例报告。
Case report on interaction of warfarin with herbal medicine "kadha".
作者信息
Premchand Rajendra Kumar, Samnani Nikita
机构信息
Department of Cardiology, Krishna Institute of Medical Sciences, Secunderabad, 500003, Telangana, India.
出版信息
IHJ Cardiovasc Case Rep. 2021 May-Aug;5(2):116-118. doi: 10.1016/j.ihjccr.2021.06.001. Epub 2021 Jun 8.
Abstract
With the increase in the number of COVID-19 cases worldwide, and a lack of proper preventive and therapeutic treatment, herbal medicine is frequently used by many people to increase the immune status of the body. We describe a case of a 56 year-old-man stabilized on warfarin (7 mg daily) from 12 years, experienced an elevated international normalized ratio (INR) of 5.45 after the consumption of an Indian traditional herbal drink "kadha" as a precautionary measure to prevent COVID-19 infection.
摘要
随着全球新冠病毒肺炎（COVID-19）病例数的增加，且缺乏适当的预防和治疗方法，许多人经常使用草药来增强身体的免疫状态。我们描述了一例56岁男性患者的病例，该患者服用华法林（每日7毫克）已达12年，病情稳定，但在饮用一种印度传统草药饮品“卡达”以预防COVID-19感染后，国际标准化比值（INR）升至5.45。
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4
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