Hull H F, Montes J M, Hays P C, Lucero R L
Pediatrics. 1985 Oct;76(4):518-23.
An outbreak of measles occurred in a municipal school system which had reported 98% of students immunized against measles. A case-control study was conducted to determine reasons for vaccine failure. Vaccine failure was associated with immunizations that could not be documented in the provider's records. Among children with provider-documented immunization, vaccine failure was associated with vaccination at 12 to 14 months of age with an odds ratio of 4.73. Among children vaccinated at 15 months or older, vaccine failure was not associated with time elapsed since vaccination. Studies should be conducted to determine whether unreliable immunization records are a more widespread problem. Further consideration should be given to routine revaccination of children previously vaccinated at 12 to 14 months of age.
在一个曾报告98%的学生接种过麻疹疫苗的市立学校系统中发生了麻疹疫情。开展了一项病例对照研究以确定疫苗接种失败的原因。疫苗接种失败与医疗服务提供者记录中无法证实的免疫接种有关。在有医疗服务提供者记录的免疫接种儿童中，疫苗接种失败与12至14个月龄时接种疫苗有关，比值比为4.73。在15个月及以上接种疫苗的儿童中，疫苗接种失败与接种疫苗后的时间间隔无关。应开展研究以确定不可靠的免疫记录是否是一个更广泛存在的问题。应进一步考虑对先前在12至14个月龄时接种过疫苗的儿童进行常规再接种。
