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[各种胶原蛋白制剂止血特性的生物学测试]

[Biological testing of hemostatic properties of various collagen preparations].

作者信息

Staniszewska-Kuś J

出版信息

Polim Med. 1985;15(1-2):21-34.

PMID:4048019
Abstract

In experiments on animals a method of studying electrostatic and hemostatic properties of collagens was worked out. Following hemostatic collagen sponges were used: Superstat (Interface Biomedical Laboratories Corporation, USA), Hemostatic Felt (B. Braun, BRD), collagen sponge and collagen foil (Central Tissue Bank of Transplantation Institute, Medical Academy, Warsaw). Biological experiments were performed on rabbits in 4 groups, depending of the implanted material. Basing on surgical macro- and microscopic evaluation it was found that collagen preparations used in the experiments shorten the duration of bleeding of damaged liver, and that biological reactivity of studied collagen preparations is proportional to the duration of their resorption time in tissues. The shortest resorption time gave the Superstat.

摘要

在动物实验中,研究人员制定了一种研究胶原蛋白静电和止血特性的方法。使用了以下止血胶原蛋白海绵:Superstat(美国Interface Biomedical Laboratories Corporation公司)、止血毡(德国贝朗公司,德国)、胶原蛋白海绵和胶原蛋白箔(华沙医学院移植研究所中央组织库)。根据植入材料的不同,对4组兔子进行了生物学实验。基于手术宏观和微观评估发现,实验中使用的胶原蛋白制剂缩短了受损肝脏的出血时间,并且所研究的胶原蛋白制剂的生物反应性与其在组织中的吸收时间成正比。Superstat的吸收时间最短。

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