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畸胎瘤血栓形成:一种通常为良性肿瘤的罕见并发症。

Thrombosis of a Teratoma: An Unusual Complication of a Usually Benign Tumor.

作者信息

Warner Alexander, Sharm Rohan, Arora Vishal, Alkhatib Deya, Kuckelman John, Gallo Dominic, Bailey Caryl

机构信息

Department of Medicine, Medical College of Georgia, Augusta, Georgia, USA.

Department of Medicine, Medical College of Georgia, Augusta, Georgia, USA.

出版信息

JACC Case Rep. 2025 Jun 4;30(13):104147. doi: 10.1016/j.jaccas.2025.104147.

DOI:10.1016/j.jaccas.2025.104147
PMID:40480741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12235153/
Abstract

BACKGROUND

Teratomas manifest as anterior mediastinal masses in young adults with excellent prognosis after surgical resection. However, given their mediastinal location, these masses can cause life-threatening complications and require challenging surgical resections.

CASE SUMMARY

A 22-year-old man was referred for persistent dyspnea with a mediastinal mass. A venous clot in transit resulted in a right atrial mass and bilateral pulmonary emboli, which prevented initial surgical intervention. The use of novel percutaneous techniques reduced his surgical risk and allowed for safe resection of the mass.

DISCUSSION

Pulmonary emboli increase perioperative mortality, but there are no definitive guidelines for their management. This case highlights the use of a multidisciplinary team and novel percutaneous therapies for perioperative pulmonary emboli and right atrial mass management.

TAKE-HOME MESSAGES: This case demonstrates the use of percutaneous techniques for perioperative management of a right atrial mass and pulmonary emboli. Percutaneous options should be considered in the setting of an initially prohibitive surgical risk.

摘要

背景

畸胎瘤在年轻成年人中表现为前纵隔肿块,手术切除后预后良好。然而,鉴于其纵隔位置,这些肿块可导致危及生命的并发症,并且需要具有挑战性的手术切除。

病例摘要

一名22岁男性因持续性呼吸困难伴纵隔肿块前来就诊。移动性静脉血栓导致右心房肿块和双侧肺栓塞,从而妨碍了最初的手术干预。新型经皮技术的应用降低了他的手术风险,并使得肿块得以安全切除。

讨论

肺栓塞会增加围手术期死亡率,但对于其管理尚无明确的指南。本病例突出了多学科团队以及新型经皮治疗方法在围手术期肺栓塞和右心房肿块管理中的应用。

经验教训

本病例展示了经皮技术在右心房肿块和肺栓塞围手术期管理中的应用。在初始手术风险过高的情况下,应考虑经皮治疗方案。

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本文引用的文献

1
Outcomes in High-Risk Pulmonary Embolism Patients Undergoing FlowTriever Mechanical Thrombectomy or Other Contemporary Therapies: Results From the FLAME Study.血流导向装置机械血栓切除术或其他当代疗法治疗高危肺栓塞患者的结局:来自 FLAME 研究的结果。
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Surgical Management and Mechanical Circulatory Support in High-Risk Pulmonary Embolisms: Historical Context, Current Status, and Future Directions: A Scientific Statement From the American Heart Association.高危肺栓塞的外科治疗与机械循环支持:历史背景、现状与未来方向:美国心脏协会科学声明
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Endovascular Removal of Thrombus and Right Heart Masses Using the AngioVac System: Results of 234 Patients from the Prospective, Multicenter Registry of AngioVac Procedures in Detail (RAPID).血管内血栓和右心肿块清除术:AngioVac 系统的 234 例患者的前瞻性、多中心 AngioVac 手术注册研究(RAPID)详细结果。
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Perioperative Acute Pulmonary Embolism: A Concise Review with Emphasis on Multidisciplinary Approach.围手术期急性肺栓塞:以多学科方法为重点的简要综述
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Surgical treatment of benign mediastinal teratoma: summary of experience of 108 cases.良性纵隔畸胎瘤的外科治疗:108例经验总结
J Cardiothorac Surg. 2020 Feb 17;15(1):36. doi: 10.1186/s13019-020-1075-8.
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Distribution of Mediastinal Lesions Across Multi-Institutional, International, Radiology Databases.多机构、国际放射学数据库中纵隔病变的分布情况
J Thorac Oncol. 2020 Apr;15(4):568-579. doi: 10.1016/j.jtho.2019.12.108. Epub 2019 Dec 20.
8
Mediastinal mature teratoma: imaging features.纵隔成熟畸胎瘤:影像学特征
AJR Am J Roentgenol. 1997 Oct;169(4):985-90. doi: 10.2214/ajr.169.4.9308448.