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[大鼠类固醇生成器官对血浆脂蛋白的摄取]

[Plasma lipoprotein absorption by steroid-producing organs in the rat].

作者信息

Poliakov L M, Panin L E

出版信息

Probl Endokrinol (Mosk). 1985 Jul-Aug;31(4):72-5.

PMID:4048102
Abstract

A study was made of the blood plasma iodinated lipoprotein (LP) absorption by the organs and tissues of rats following i.v. injection. The adrenals and ovaries were shown to effectively absorb high density lipoproteins (HDL) as compared to the liver, spleen, kidneys, heart and lungs. HDL absorption reached its maximum 30 min after LP injection. Six hours later the adrenal tissue radioactivity level decreased by 30% and after 12 h 3-fold. The time-course of HDL absorption by the ovaries was characterized by a slow increase in radioactivity after 6 h and a gradual decrease of the label index after 12 h. Differences in HDL absorption by the adrenals and ovaries reflected some functional features of these steroid producing organs.

摘要

对大鼠静脉注射后,其器官和组织对血浆碘化脂蛋白(LP)的吸收情况进行了研究。结果显示,与肝脏、脾脏、肾脏、心脏和肺相比,肾上腺和卵巢能有效吸收高密度脂蛋白(HDL)。LP注射后30分钟,HDL吸收达到最大值。6小时后,肾上腺组织放射性水平下降30%,12小时后下降了3倍。卵巢对HDL吸收的时间进程表现为6小时后放射性缓慢增加,12小时后标记指数逐渐下降。肾上腺和卵巢对HDL吸收的差异反映了这些类固醇生成器官的一些功能特征。

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