Unger Elizabeth R
Chronic Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention.
Am J Health Promot. 2025 Jul;39(6):960-965. doi: 10.1177/08901171241308066b. Epub 2025 Jun 8.
A link between infection and chronic illness has been recognized, along with the complexities of interactions between pathogen, environment, host genetics, route of exposure, and timing of outcomes. The COVID-19 pandemic has brought this issue to the forefront and Long COVID is recognized to be an infection associated chronic condition. However, given the wide range of Long COVID presentations, the singular expression gives a false sense of simplicity. Long COVID is best considered as a group of infection associated conditions requiring developing research studies and treatment trials that address the inherent heterogeneity.
感染与慢性病之间的联系已得到认可，同时也认识到病原体、环境、宿主遗传学、接触途径和结果发生时间之间相互作用的复杂性。新冠疫情使这个问题成为焦点，长期新冠被认为是一种与感染相关的慢性病。然而，鉴于长期新冠的表现形式多种多样，单一的表述给人一种简单化的错觉。最好将长期新冠视为一组与感染相关的病症，需要开展研究和治疗试验来应对其内在的异质性。
