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免疫功能正常患者的肺诺卡菌病:一例报告

Pulmonary Nocardiosis in an Immunocompetent Patient: A Case Report.

作者信息

Ibrahimi Reza, Poursadegh Farid, Mozdourian Mahnaz, Rezaeetalab Fariba, Emamdadi Zohre, Yousefabadi Sahar Arab, Samadi Sara

机构信息

Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.

Lung Diseases Research Center Mashhad University of Medical Sciences Mashhad Iran.

出版信息

Clin Case Rep. 2025 Jun 5;13(6):e70505. doi: 10.1002/ccr3.70505. eCollection 2025 Jun.

Abstract

The patient, a 56-year-old female with a history of childhood bronchiectasis and controlled hypertension, presented with fever, cough, and hemoptysis. Despite initial treatment for exacerbation of bronchiectasis, her condition worsened, leading to sepsis. Blood tests revealed leukocytosis and elevated CRP. Lung HRCT showed necrotic consolidation and nodules in the left and right lung, suggestive of necrotizing pneumonia. Bronchoscopy revealed species, leading to intravenous co-trimoxazole treatment. After a week in ICU, the patient improved and was discharged with oral co-trimoxazole. The patient remained free of relapse during a 6-month follow-up period, with no CNS or cutaneous involvement detected.

摘要

该患者为一名56岁女性,有儿童期支气管扩张病史且高血压病情得到控制,出现发热、咳嗽和咯血症状。尽管最初对支气管扩张加重进行了治疗,但其病情仍恶化,导致脓毒症。血液检查显示白细胞增多和C反应蛋白升高。肺部高分辨率CT显示左肺和右肺有坏死性实变和结节,提示坏死性肺炎。支气管镜检查发现了[具体物种未提及],遂进行静脉复方新诺明治疗。在重症监护病房治疗一周后,患者病情好转,出院时带口服复方新诺明。在6个月的随访期内,患者未复发,未检测到中枢神经系统或皮肤受累情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed52/12141085/c26ad87c9021/CCR3-13-e70505-g003.jpg

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