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可脱性球囊栓塞术治疗外伤性颈内动脉海绵窦瘘的疗效

Outcome of Detachable Balloon Embolization in Traumatic Carotid Cavernous Fistula.

作者信息

Rujimethapass Sujin

机构信息

Division of Neurosurgery, Department of Surgery, College of Medicine, Rangsit University, Rajavithi Hospital, Bangkok, Thailand.

出版信息

Asian J Neurosurg. 2025 Mar 18;20(2):330-336. doi: 10.1055/s-0045-1805017. eCollection 2025 Jun.

DOI:10.1055/s-0045-1805017
PMID:40485805
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12136968/
Abstract

This article evaluates the outcomes and efficacy of detachable balloon embolization by single balloon delivery catheter, while identifying factors associated with successful embolization in traumatic carotid cavernous fistula (TCCF) patients.  We retrospectively collected data of TCCF patients who underwent detachable balloon embolization during March 2020 to April 2024. All cases utilized a single balloon delivery catheter for detachable balloon deployment (GOLDBAL, BALT Extrusion, France). We analyzed demographic, clinical, imaging, and angiographic data, including outcomes, complications, and factors associated with successful embolization.  Thirty patients were treated with detachable balloon embolization. The mean age of the patients was 41.1 years (range 17-65 years). The median duration of symptom was 2.0 months (range 0.25-60 months). The most common mechanism of injury is motorcycle accident (83.3%). Nearly all patients had eye redness and proptosis. Angiographic data indicated 29 patients (96.7%) had drainage to the inferior petrosal sinus, 28 (93.3%) had drainage to the superior ophthalmic vein, and 8 (26.7%) had drainage to the superior petrosal sinus. Five cases (16.7%) were classified as small-sized fistula, 19 (63.3%) as medium-sized, and 6 (20%) as large-sized. Regarding the location of the fistula, 8 cases (26.7%) were found in the horizontal segment, while 22 cases (73.3%) were located in the ascending or genu segment of the cavernous internal carotid artery (ICA). Among the 24 patients (80%) who underwent successful embolization, the ICA was preserved in 23 out of 24 patients (95.8%). The remaining patient had ICA occlusion but exhibited no clinical symptoms. Residual cavernous aneurysm was found in two patients, one patient had persistent cranial nerve deficit, while the other was asymptomatic. Statistical analysis demonstrated a significant difference was associated with the fistula location at the ascending or genu segment of the cavernous ICA in relation to successful embolization  Despite the availability of several endovascular treatment options for TCCF, using detachable balloon embolization is a relatively straightforward procedure. When combined with a thorough understanding of cavernous sinus anatomy, this approach can significantly enhance the occlusion rate and preserve ICA patency while minimizing complications, particularly when the fistula is located at the ascending or genu segment of the cavernous ICA.

摘要

本文评估了使用单球囊输送导管进行可脱性球囊栓塞术的疗效及结果,同时确定了创伤性颈内动脉海绵窦瘘(TCCF)患者成功栓塞的相关因素。

我们回顾性收集了2020年3月至2024年4月期间接受可脱性球囊栓塞术的TCCF患者的数据。所有病例均使用单球囊输送导管进行可脱性球囊置入(GOLDBAL,法国BALT Extrusion公司)。我们分析了人口统计学、临床、影像学和血管造影数据,包括治疗结果、并发症以及与成功栓塞相关的因素。

30例患者接受了可脱性球囊栓塞术治疗。患者的平均年龄为41.1岁(范围17 - 65岁)。症状的中位持续时间为2.0个月(范围0.25 - 60个月)。最常见的损伤机制是摩托车事故(83.3%)。几乎所有患者都有眼红和眼球突出症状。血管造影数据显示,29例患者(96.7%)向岩下窦引流,28例(93.3%)向上眼静脉引流,8例(26.7%)向岩上窦引流。5例(16.7%)被分类为小型瘘,19例(63.3%)为中型瘘,6例(20%)为大型瘘。关于瘘的位置,8例(26.7%)位于水平段,而22例(73.3%)位于海绵窦段颈内动脉(ICA)的上升段或膝段。在24例(80%)成功栓塞的患者中,24例中有23例(95.8%)ICA得以保留。其余1例患者ICA闭塞但无临床症状。2例患者发现有残留海绵窦动脉瘤,1例患者有持续性颅神经功能缺损,另例患者无症状。统计分析表明,海绵窦段ICA上升段或膝段的瘘位置与成功栓塞存在显著差异。

尽管TCCF有多种血管内治疗选择,但使用可脱性球囊栓塞术是一种相对简单的手术。当结合对海绵窦解剖结构的透彻理解时,这种方法可以显著提高闭塞率并保留ICA通畅性,同时将并发症降至最低,特别是当瘘位于海绵窦段ICA上升段或膝段时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5bd/12136968/14f427879786/10-1055-s-0045-1805017-i24100014-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5bd/12136968/a3602526d041/10-1055-s-0045-1805017-i24100014-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5bd/12136968/a17c8e624bf2/10-1055-s-0045-1805017-i24100014-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5bd/12136968/14f427879786/10-1055-s-0045-1805017-i24100014-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5bd/12136968/a3602526d041/10-1055-s-0045-1805017-i24100014-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5bd/12136968/a17c8e624bf2/10-1055-s-0045-1805017-i24100014-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5bd/12136968/14f427879786/10-1055-s-0045-1805017-i24100014-3.jpg

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本文引用的文献

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Flow diversion in direct carotid-cavernous fistula refractory to multiple coil embolizations: case report and review of the literature.直接颈动脉-海绵窦瘘多次线圈栓塞治疗无效的血流转向:病例报告及文献复习。
J Stroke Cerebrovasc Dis. 2022 Dec;31(12):106840. doi: 10.1016/j.jstrokecerebrovasdis.2022.106840. Epub 2022 Oct 23.
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First line Treatment of Traumatic Carotid Cavernous Fistulas Using Covered Stents at Level 1 Regional Trauma Center.
在一级区域创伤中心使用覆膜支架治疗创伤性颈动脉海绵窦瘘的一线治疗
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