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[伴有巨大体感诱发电位的肌阵挛的罕见病因:溴甲烷中毒。关于1例单侧优势病例]

[Rare cause of myoclonus with giant SEP's: methyl bromide poisoning. Apropos of a case with unilateral predominance].

作者信息

Audry D, Soichot P, Giard M H, Mauguière F

出版信息

Rev Electroencephalogr Neurophysiol Clin. 1985 Jul;15(1):45-52. doi: 10.1016/s0370-4475(85)80034-4.

Abstract

Giant and asymmetric SEPs were recorded in a patient with predominantly unilateral, spontaneous and intention myoclonus due to voluntary intoxication with methyl bromide as soon as day 3 after intoxication. The N10 Erb's point potential, cervical N13 and scalp recorded P15 potentials were found to be normal in latency, morphology and amplitude. The somesthetic informations could be considered as normally processed up to the subcortical levels of the somatosensory pathways. The parietal cortical potentials N20 and P25 and the frontal cortical potentials P22 and N30, contralateral to myoclonus, were abnormally large. This suggests that myoclonus could be related with an abnormal reactivity of somatomotor and somatosensory cortices to the afferent volleys triggered by voluntary movements. The prerolandic components P22 and N30 were found to be relatively more enhanced than the parietal N20 and P15.

摘要

在一名因自愿摄入甲基溴而导致主要为单侧、自发性和意向性肌阵挛的患者中,中毒后第3天就记录到了巨大且不对称的体感诱发电位(SEP)。发现N10(Erb点电位)、颈部N13以及头皮记录到的P15电位在潜伏期、形态和波幅方面均正常。可以认为,直到躯体感觉通路的皮质下水平,躯体感觉信息的处理都是正常的。与肌阵挛对侧的顶叶皮质电位N20和P25以及额叶皮质电位P22和N30异常增大。这表明肌阵挛可能与躯体运动和躯体感觉皮质对自愿运动触发的传入冲动的异常反应有关。发现中央前回成分P22和N30比顶叶的N20和P15相对增强得更多。

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