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连接外科肿瘤学与个性化医疗:人工智能和机器学习在胸外科中的作用

Bridging surgical oncology and personalized medicine: the role of artificial intelligence and machine learning in thoracic surgery.

作者信息

Ijlal Aisha, Mumtaz Hassan, Hassan Syed Muhammad, Mustafa Qurat-Ul-Ain, Khalil Ahmed Bazil Bin, Ali Umna, Tanveer Zainab Khayal, Sajjad Laiba

机构信息

Jinnah Sindh Medical University, Karachi,Pakistan.

BPP University, London, UK.

出版信息

Ann Med Surg (Lond). 2025 Apr 22;87(6):3566-3572. doi: 10.1097/MS9.0000000000003302. eCollection 2025 Jun.

DOI:10.1097/MS9.0000000000003302
PMID:40486596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12140760/
Abstract

Lung cancer remains the leading cause of cancer-related deaths globally, often detected in advanced stages with poor prognosis. While surgical resection is the mainstay of curative treatment, early detection remains a significant challenge. Advances in personalized medicine, including genomic profiling and low-dose CT scans, have led to more tailored therapies, offering improved outcomes. Integrating artificial intelligence (AI) and machine learning (ML) into oncology has the potential to revolutionize lung cancer management by enhancing early detection, improving treatment precision, and supporting surgical decision-making. AI-driven technologies, such as deep learning algorithms and predictive models, have demonstrated effectiveness in identifying lung nodules, predicting immunotherapy response, and reducing diagnostic errors. Additionally, AI-powered robotics have contributed to improved surgical precision and better patient recovery. However, the widespread adoption of AI in clinical practice faces challenges, including data standardization, ethical concerns, and the need for robust validation. This study explores the question: How can AI and ML optimize thoracic surgical oncology by improving early detection, enhancing surgical precision, and enabling personalized care? This review highlights the significance of AI and ML in thoracic surgery and oncology, discussing their current applications, limitations, and future potential to advance personalized cancer care and improve patient outcomes.

摘要

肺癌仍然是全球癌症相关死亡的主要原因,通常在晚期才被发现,预后较差。虽然手术切除是根治性治疗的主要手段,但早期检测仍然是一项重大挑战。个性化医疗的进展,包括基因组分析和低剂量CT扫描,已带来了更具针对性的治疗方法,改善了治疗效果。将人工智能(AI)和机器学习(ML)整合到肿瘤学中,有可能通过加强早期检测、提高治疗精度和支持手术决策,彻底改变肺癌的治疗管理。诸如深度学习算法和预测模型等人工智能驱动的技术,已在识别肺结节、预测免疫治疗反应以及减少诊断错误方面显示出有效性。此外,人工智能驱动的机器人技术有助于提高手术精度和促进患者更好地康复。然而,人工智能在临床实践中的广泛应用面临挑战,包括数据标准化、伦理问题以及进行有力验证的必要性。本研究探讨了这样一个问题:人工智能和机器学习如何通过改善早期检测、提高手术精度以及实现个性化护理来优化胸外科肿瘤学?这篇综述强调了人工智能和机器学习在胸外科手术和肿瘤学中的重要性,讨论了它们目前的应用、局限性以及推进个性化癌症护理和改善患者治疗效果的未来潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d6/12140760/dcc0ad9e80ba/ms9-87-3566-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d6/12140760/dcc0ad9e80ba/ms9-87-3566-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d6/12140760/dcc0ad9e80ba/ms9-87-3566-g001.jpg

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本文引用的文献

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Enhancing Thoracic Surgery with AI: A Review of Current Practices and Emerging Trends.人工智能在胸外科中的应用:现状与新兴趋势综述。
Curr Oncol. 2024 Oct 17;31(10):6232-6244. doi: 10.3390/curroncol31100464.
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Implementing machine learning to predict survival outcomes in patients with resected pulmonary large cell neuroendocrine carcinoma.运用机器学习预测接受手术切除的肺大细胞神经内分泌癌患者的生存结局。
Expert Rev Anticancer Ther. 2024 Oct;24(10):1041-1053. doi: 10.1080/14737140.2024.2401446. Epub 2024 Sep 9.
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Evaluation of robotic-assisted navigation system for CT-guided thoracic and abdominal lesion puncture: A prospective clinical study.
机器人辅助导航系统在 CT 引导下胸部和腹部病变穿刺中的评估:一项前瞻性临床研究。
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Artificial intelligence-assisted augmented reality robotic lung surgery: Navigating the future of thoracic surgery.人工智能辅助增强现实机器人肺手术:引领胸外科手术的未来。
JTCVS Tech. 2024 May 3;26:121-125. doi: 10.1016/j.xjtc.2024.04.011. eCollection 2024 Aug.
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Multidisciplinary Surgical Approach Using Augmented Reality Preplanning for Resection of Giant Thoracic Schwannoma With Robotic-Assisted Thoracoscopic Mobilization.多学科联合手术方法,使用增强现实技术进行术前规划,辅助机器人胸腔镜下进行胸 schwannoma 切除。
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A System for Mixed-Reality Holographic Overlays of Real-Time Rendered 3D-Reconstructed Imaging Using a Video Pass-through Head-Mounted Display-A Pathway to Future Navigation in Chest Wall Surgery.一种使用视频透视头戴式显示器进行实时渲染的3D重建成像的混合现实全息叠加系统——胸壁手术未来导航的途径。
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Recent advances in lung cancer research: unravelling the future of treatment.肺癌研究的最新进展:揭示治疗的未来。
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The future of artificial intelligence in thoracic surgery for non-small cell lung cancer treatment a narrative review.人工智能在非小细胞肺癌治疗的胸外科手术中的未来:一项叙述性综述
Front Oncol. 2024 Feb 13;14:1347464. doi: 10.3389/fonc.2024.1347464. eCollection 2024.
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