血流限制联合神经肌肉电刺激对膝关节功能的影响：一项系统评价与荟萃分析。
The effect of blood flow restriction combined with neuromuscular electrical stimulation on knee joint function: A systematic review and meta-analysis.
作者信息
Herbawi Fahed, Daami Asmaa, Ishtayah Haneen, Al Deen Hiba Fakher, Nofal Maha, Zaid Shaimaa, Lozano-Lozano Mario, Fernandez-Lao Carolina
机构信息
Department of Applied and Allied Medical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Department of Physical Therapy, Health Science Faculty, University of Granada, Avda de la Ilustración 60, 18016, Granada, Spain.
出版信息
J Orthop. 2025 May 5;65:155-166. doi: 10.1016/j.jor.2025.05.012. eCollection 2025 Jul.
OBJECTIVE
To determine whether the combined application of blood flow restriction and neuromuscular electrical stimulation significantly affects quadriceps strength, hypertrophy, pain, and fatigue.
DESIGN
Systematic review with meta-analysis.
LITERATURE SEARCH
PubMed, Scopus, and Web of Science from inception to November 2023.
STUDY SELECTION CRITERIA
Randomized and non-randomized full-text human clinical trials published in English investigating the combination between blood flow restriction and neuromuscular electrical stimulation on knee joint.
DATA SYNTHESIS
The correlation data was pooled across studies using a random effects model. Cohen's D was calculated for each original study and an overall estimator, and a two-sided p value < 0.05 was considered statistically significant.
RESULTS
Out of 294 records, nine studies with 257 participants were included in the systematic review. A meta-analysis revealed no significant differences in quadriceps strength at two, 3, and 6 weeks. Similarly, it was also shown in hypertrophy at 7-15 min, 2, and 6 weeks.
CONCLUSION
The blood flow restriction combined with neuromuscular electrical stimulation had no additional effect to the original isolated techniques on quadriceps strength and hypertrophy. Moreover, causes higher pain and fatigue levels after its use.
目的
确定血流限制与神经肌肉电刺激联合应用是否会显著影响股四头肌力量、肥大、疼痛和疲劳。
设计
系统评价与荟萃分析。
文献检索
检索了从创刊至2023年11月的PubMed、Scopus和Web of Science数据库。
研究选择标准
以英文发表的关于膝关节血流限制与神经肌肉电刺激联合应用的随机和非随机全文人类临床试验。
数据合成
使用随机效应模型对各研究的相关数据进行汇总。计算每项原始研究和总体估计值的Cohen's D，双侧p值<0.05被认为具有统计学意义。
结果
在294条记录中，有9项研究（共257名参与者）被纳入系统评价。荟萃分析显示，在2周、3周和6周时股四头肌力量无显著差异。同样，在7 - 15分钟、2周和6周时的肥大情况也如此。
结论
血流限制与神经肌肉电刺激联合应用对股四头肌力量和肥大方面，相较于单独使用原始技术并无额外效果。此外，使用后会导致更高水平的疼痛和疲劳。
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