Carskadon M A, Dement W C
Sleep. 1985;8(3):207-21. doi: 10.1093/sleep/8.3.207.
Sleep, performance, and sleepiness were assessed in 10 elderly volunteers (8 women, 2 men; aged 61-77 years) before, during, and after 38 h of sleep loss. Recovery night 1 sleep showed increased total sleep and stages 3 and 4 sleep and decreased stage 1 sleep, wakefulness, brief arousals, and latency to stages 3 and 4 sleep. An increase in stage 4 sleep persisted to the second recovery night. Increased arousal threshold was suggested by a lengthening of respiratory events and a reduction in arousals associated with leg movements. Performance was impaired during sleep loss, associated with an increased tendency to fall asleep. Reported sleepiness increased, except in three subjects who denied sleepiness. Latency to sleep onset declined. All measures returned to basal values after a night of sleep. Sleep in one volunteer failed to respond to sleep loss. With this exception, the response was similar to that reported in younger volunteers, although shorter-lived.
在10名老年志愿者(8名女性,2名男性;年龄61 - 77岁)睡眠剥夺38小时之前、期间和之后,对他们的睡眠、表现和嗜睡情况进行了评估。恢复第一晚的睡眠显示总睡眠时间增加,3期和4期睡眠增加,1期睡眠、清醒时间、短暂觉醒以及进入3期和4期睡眠的潜伏期减少。4期睡眠的增加持续到第二个恢复夜晚。呼吸事件延长以及与腿部运动相关的觉醒减少表明觉醒阈值增加。在睡眠剥夺期间表现受损,伴有入睡倾向增加。报告的嗜睡情况增加,但有三名受试者否认嗜睡。入睡潜伏期缩短。经过一晚睡眠后,所有指标均恢复到基础值。一名志愿者的睡眠对睡眠剥夺无反应。除了这个例外,反应与年轻志愿者报告的相似,尽管持续时间较短。