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血糖控制管理中糖尿病的各种分类方法。

Various classification methods for diabetes mellitus in the management of blood glucose control.

作者信息

Jiang Qing, Hu Yun, Ma Jian-Hua

机构信息

Department of Endocrinology, The Affiliated Geriatric Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu Province, China.

Department of Endocrinology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214000, Jiangsu Province, China.

出版信息

World J Diabetes. 2025 May 15;16(5):103316. doi: 10.4239/wjd.v16.i5.103316.

DOI:10.4239/wjd.v16.i5.103316
PMID:40487606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12142176/
Abstract

In the era of precision medicine, the classification of diabetes mellitus has evolved beyond the traditional categories. Various classification methods now account for a multitude of factors, including variations in specific genes, type of β-cell impairment, degree of insulin resistance, and clinical characteristics of metabolic profiles. Improved classification methods enable healthcare providers to formulate blood glucose management strategies more precisely. Applying these updated classification systems, will assist clinicians in further optimising treatment plans, including targeted drug therapies, personalized dietary advice, and specific exercise plans. Ultimately, this will facilitate stricter blood glucose control, minimize the risks of hypoglycaemia and hyperglycaemia, and reduce long-term complications associated with diabetes.

摘要

在精准医学时代,糖尿病的分类已超越传统类别。现在各种分类方法考虑了众多因素,包括特定基因的变异、β细胞损伤类型、胰岛素抵抗程度以及代谢谱的临床特征。改进的分类方法使医疗保健提供者能够更精确地制定血糖管理策略。应用这些更新的分类系统,将有助于临床医生进一步优化治疗方案,包括靶向药物治疗、个性化饮食建议和特定的运动计划。最终,这将有助于更严格地控制血糖,将低血糖和高血糖的风险降至最低,并减少与糖尿病相关的长期并发症。

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本文引用的文献

1
Association of the glycemic background patterns and the diabetes management efficacy in poorly controlled type 2 diabetes.血糖背景模式与血糖控制不佳的2型糖尿病患者糖尿病管理疗效的关联
World J Diabetes. 2025 Jan 15;16(1):98322. doi: 10.4239/wjd.v16.i1.98322.
2
Genetic Subtypes of Prediabetes, Healthy Lifestyle, and Risk of Type 2 Diabetes.糖尿病前期的遗传亚型、健康生活方式与 2 型糖尿病风险。
Diabetes. 2024 Jul 1;73(7):1178-1187. doi: 10.2337/db23-0699.
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Systematic immune cell dysregulation and molecular subtypes revealed by single-cell RNA-seq of subjects with type 1 diabetes.单细胞 RNA-seq 揭示 1 型糖尿病患者的系统性免疫细胞失调和分子亚型。
Genome Med. 2024 Mar 27;16(1):45. doi: 10.1186/s13073-024-01300-z.
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Risk of Diabetic Retinopathy According to Subtype of Type 2 Diabetes.根据 2 型糖尿病的亚型评估糖尿病视网膜病变的风险。
Diabetes. 2024 Jun 1;73(6):977-982. doi: 10.2337/db24-0016.
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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.2 型糖尿病病理生理学异质性的遗传驱动因素。
Nature. 2024 Mar;627(8003):347-357. doi: 10.1038/s41586-024-07019-6. Epub 2024 Feb 19.
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Diabetes Care. 2024 Jan 1;47(Suppl 1):S20-S42. doi: 10.2337/dc24-S002.
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Serum cystatin C for risk stratification of prediabetes and diabetes populations.血清胱抑素 C 用于预测糖尿病前期和糖尿病患者的危险分层。
Diabetes Metab Syndr. 2023 Nov;17(11):102882. doi: 10.1016/j.dsx.2023.102882. Epub 2023 Oct 23.
8
Understanding diabetes heterogeneity: key steps towards precision medicine in diabetes.了解糖尿病异质性:迈向糖尿病精准医学的关键步骤。
Lancet Diabetes Endocrinol. 2023 Nov;11(11):848-860. doi: 10.1016/S2213-8587(23)00159-6. Epub 2023 Oct 4.
9
Discovery of ecnoglutide - A novel, long-acting, cAMP-biased glucagon-like peptide-1 (GLP-1) analog.发现 ecno 利拉鲁肽 - 一种新型长效、cAMP 偏向性胰高血糖素样肽-1(GLP-1)类似物。
Mol Metab. 2023 Sep;75:101762. doi: 10.1016/j.molmet.2023.101762. Epub 2023 Jun 24.
10
Oral insulin delivery: Barriers, strategies, and formulation approaches: A comprehensive review.口服胰岛素递药系统:障碍、策略及制剂方法:全面综述。
Int J Biol Macromol. 2023 Jul 1;242(Pt 3):125114. doi: 10.1016/j.ijbiomac.2023.125114. Epub 2023 May 31.