Decates Tom S, Schoonen Tamar, Onderdijk Armanda J, van Leerdam Martin, Velthuis Peter J
From the Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands.
Bare Statistics, Stompetoren, The Netherlands.
Plast Reconstr Surg Glob Open. 2025 Jun 6;13(6):e6815. doi: 10.1097/GOX.0000000000006815. eCollection 2025 Jun.
Gluteal or hip augmentation with nonresorable (permanent) fillers can lead to complications. Nonsurgical treatment options are unclear and are mainly based on case reports. This study aimed to examine which treatment option is the better choice for patients with complications after permanent fillers in the buttocks.
In this retrospective cohort study, the data of patients visiting our hospital clinic with complications between 2016 and 2021 after gluteal or hip augmentation with fillers were analyzed. Contingency table analyses were conducted to determine which of the 5 types of treatments, minocycline, surgery, intralesional laser treatment (ILT), pressure garments, and omega-3 supplements, were related to pain relief and softening of the nodules.
Seventy-two patients (69 women and 3 men; mean age, 39 y) were selected. Inclusion criteria were men and women older than 18 years of age with complications after gluteal or thigh augmentation with permanent fillers. Filler material was mainly found in the buttocks and hips. Treatment options were antibiotics, surgery, laser, pressure garment, and omega-3 supplements. Pain relief was reported in 36 of the 42 responders. Softening of the nodules appeared to be positively associated with ILT (odds ratio = 20.25).
The most common complication was subcutaneous inflammation (panniculitis) in the buttocks and hips. Most patients reported reduced pain and softening of the nodules after treatment. The latter outcome appears to be related to the ILT. Considering the information in the literature and our findings, a step-by-step treatment protocol was developed.
使用不可吸收（永久性）填充剂进行臀部或髋部增大术可能会导致并发症。非手术治疗方案尚不明确，且主要基于病例报告。本研究旨在探讨哪种治疗方案对于臀部使用永久性填充剂后出现并发症的患者是更好的选择。
在这项回顾性队列研究中，分析了2016年至2021年间因使用填充剂进行臀部或髋部增大术后出现并发症而到我院门诊就诊的患者数据。进行列联表分析以确定5种治疗方法中的哪一种，即米诺环素、手术、病灶内激光治疗（ILT）、压力衣和ω-3补充剂，与疼痛缓解和结节软化有关。
共纳入72例患者（69例女性和3例男性；平均年龄39岁）。纳入标准为年龄大于18岁、在使用永久性填充剂进行臀部或大腿增大术后出现并发症的男性和女性。填充材料主要见于臀部和髋部。治疗方案包括抗生素、手术、激光、压力衣和ω-3补充剂。42例有反应的患者中有36例报告疼痛缓解。结节软化似乎与病灶内激光治疗呈正相关（优势比=20.25）。
最常见的并发症是臀部和髋部的皮下炎症（脂膜炎）。大多数患者报告治疗后疼痛减轻且结节软化。后一结果似乎与病灶内激光治疗有关。综合文献资料和我们的研究结果，制定了一个逐步的治疗方案。
