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肺癌患者外周血中性粒细胞的细胞化学研究。

Cytochemical study of neutrophils from peripheral blood of patients with lung cancer.

作者信息

Sułowicz W

出版信息

Med Interne. 1985 Jul-Sep;23(3):195-200.

PMID:4048800
Abstract

In 32 patients with untreated lung cancer, activity of alkaline phosphatase, acid phosphatase, beta-glucuronidase and N-acetyl-beta-glucosaminidase were determined cytochemically in peripheral blood of neutrophils. The results obtained were compared with those in 40 healthy subjects. Total counts of alkaline phosphatase, acid phosphatase, beta-glucuronidase and N-acetyl-beta-glucosaminidase positive neutrophils were significantly higher in patients with lung cancer, as compared with the control group. Mean value of alkaline phosphatase activity index (Score) was significantly higher in cancer patients in comparison to the control group whereas mean values of acid phosphatase, beta-glucuronidase and N-acetyl-beta-glucosaminidase activities did not differ significantly.

摘要

对32例未经治疗的肺癌患者,采用细胞化学方法测定其外周血中性粒细胞碱性磷酸酶、酸性磷酸酶、β-葡萄糖醛酸酶和N-乙酰-β-氨基葡萄糖苷酶的活性。将所得结果与40名健康受试者的结果进行比较。与对照组相比,肺癌患者碱性磷酸酶、酸性磷酸酶、β-葡萄糖醛酸酶和N-乙酰-β-氨基葡萄糖苷酶阳性中性粒细胞的总数显著更高。与对照组相比,癌症患者碱性磷酸酶活性指数(评分)的平均值显著更高,而酸性磷酸酶、β-葡萄糖醛酸酶和N-乙酰-β-氨基葡萄糖苷酶活性的平均值没有显著差异。

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