Nikolaidou Anna, Mougkogiannis Panagiotis, Adamatzky Andrew
Unconventional Computing Laboratory, University of the West of England, Bristol BS16 1QY, U.K.
School of Architecture and Environment, University of the West of England, Coldharbour Ln, Stoke Gifford, Bristol BS16 1QY, U.K.
ACS Omega. 2025 May 20;10(21):21128-21146. doi: 10.1021/acsomega.4c09743. eCollection 2025 Jun 3.
The work introduces a composite material that combines Kombucha cellulose mats with synthetic thermal proteinoids to create electroactive biofilms, capable of sensing and computation. The synthesis of proteinoids involves heating amino acid mixtures, which leads to the formation of proto-cell structures capable of biological electrical signaling. We demonstrate that these hybrid biofilms exhibit adjustable memristive and memfractance properties, which can be utilized for unconventional computing tasks. The potential applications of living biofilms extend beyond neural interfaces, encompassing bioinspired robotics, smart wearables, adaptive biorobotic systems, and other technologies that rely on dynamic bioelectronic materials. The composite films offer a wide range of options for synthesis and performance customization. Current research is dedicated to customizing the composition, nanostructure, and integration of proteinoids in hybrid circuits to achieve specific electronic functionalities. Overall, these cross-kingdom biofilms are an intriguing category of materials that combine the unique properties of biological organisms and smart polymers. The Kombucha-proteinoid composites are a significant step forward in the development of future technologies that bridge the gap between living and artificial life systems. These composites have the remarkable ability to support cellular systems and demonstrate adaptive bioelectronic behavior.
这项工作介绍了一种复合材料，它将康普茶纤维素垫与合成热类蛋白结合起来，以制造出能够进行传感和计算的电活性生物膜。类蛋白的合成涉及加热氨基酸混合物，这会导致能够进行生物电信号传导的原细胞结构的形成。我们证明，这些混合生物膜表现出可调节的忆阻和忆抗特性，可用于非常规计算任务。活性生物膜的潜在应用不仅限于神经接口，还包括受生物启发的机器人技术、智能可穿戴设备、自适应生物机器人系统以及其他依赖动态生物电子材料的技术。复合膜为合成和性能定制提供了广泛的选择。当前的研究致力于在混合电路中定制类蛋白的组成、纳米结构和集成，以实现特定的电子功能。总的来说，这些跨领域生物膜是一类有趣的材料，它们结合了生物有机体和智能聚合物的独特特性。康普茶 - 类蛋白复合材料是未来技术发展中的重要一步，它弥合了生命系统和人工生命系统之间的差距。这些复合材料具有支持细胞系统并展示自适应生物电子行为的显著能力。
