Mougkogiannis Panagiotis, Adamatzky Andrew
Unconventional Computing Laboratory, UWE, Bristol BS16 1QY, U.K.
ACS Omega. 2024 Mar 18;9(13):15085-15100. doi: 10.1021/acsomega.3c09330. eCollection 2024 Apr 2.
Proteinoids, or thermal proteins, are amino acid polymers formed at high temperatures by nonbiological processes. The objective of this study is to examine the memfractance characteristics of proteinoids within a supersaturated hydroxyapatite solution. The ionic solution utilized for the current-voltage (-) measurements possessed an ionic strength of 0.15 mol/L, a temperature of 37 °C, and a pH value of 7.4. The - curves exhibited distinct spikes, which are hypothesized to arise from the capacitive charging and discharging of the proteinoid-hydroxyapatite media. The experimental results demonstrated a positive correlation between the concentration of proteinoids and the observed number of spikes in the - curves. This observation provides evidence in favor of the hypothesis that the spikes originate from the proteinoids' capacitive characteristics. The memfractance behavior exemplifies the capacity of proteinoids to retain electrical charge within the hydrated hydroxyapatite media. Additional investigation is required in order to comprehensively identify the memcapacitive phenomena and delve into their implications for models of protocellular membranes. In a nutshell, this study provides empirical support for the existence of capacitive membrane-memfractance mechanisms in ensembles of proteinoids.
类蛋白质，即热蛋白质，是通过非生物过程在高温下形成的氨基酸聚合物。本研究的目的是研究类蛋白质在过饱和羟基磷灰石溶液中的忆阻特性。用于电流 - 电压（-）测量的离子溶液的离子强度为0.15 mol/L，温度为37°C，pH值为7.4。-曲线呈现出明显的尖峰，据推测这是由类蛋白质 - 羟基磷灰石介质的电容性充电和放电引起的。实验结果表明类蛋白质的浓度与 - 曲线中观察到的尖峰数量之间存在正相关。这一观察结果为尖峰源自类蛋白质的电容特性这一假设提供了证据。忆阻行为例证了类蛋白质在水合羟基磷灰石介质中保留电荷的能力。为了全面识别忆容现象并深入研究它们对原始细胞膜模型的影响，还需要进一步的研究。简而言之，本研究为类蛋白质集合中电容性膜 - 忆阻机制的存在提供了实证支持。
