Nikolaidou Anna, Mougkogiannis Panagiotis, Adamatzky Andrew
Unconventional Computing Laboratory, University of the West of England, Bristol, UK.
School of Architecture and Environment, University of the West of England, Bristol, UK.
R Soc Open Sci. 2024 May 29;11(5):240238. doi: 10.1098/rsos.240238. eCollection 2024 May.
In this study, we present electroactive biofilms made from a combination of Kombucha zoogleal mats and thermal proteinoids. These biofilms have potential applications in unconventional computing and robotic skin. Proteinoids are synthesized by thermally polymerizing amino acids, resulting in the formation of synthetic protocells that display electrical signalling similar to neurons. By incorporating proteinoids into Kombucha zoogleal cellulose mats, hydrogel biofilms can be created that have the ability to efficiently transfer charges, perform sensory transduction and undergo processing. We conducted a study on the memfractance and memristance behaviours of composite biofilms, showcasing their capacity to carry out unconventional computing operations. The porous nanostructure and electroactivity of the biofilm create a biocompatible interface that can be used to record and stimulate neuronal networks. In addition to neuronal interfaces, these soft electroactive biofilms show potential as components for bioinspired robotics, smart wearables, unconventional computing devices and adaptive biorobotic systems. Kombucha-proteinoids composite films are a highly customizable material that can be synthesized to suit specific needs. These films belong to a unique category of 'living' materials, as they have the ability to support cellular systems and improve bioelectronic functionality. This makes them an exciting prospect in various applications. Ongoing efforts are currently being directed towards enhancing the compositional tuning of conductivity, signal processing and integration within hybrid bioelectronic circuits.
在本研究中，我们展示了由康普茶菌胶团垫和热聚氨基酸形成的电活性生物膜。这些生物膜在非传统计算和机器人皮肤方面具有潜在应用。热聚氨基酸可合成聚氨基酸，从而形成显示出与神经元类似电信号传导的合成原始细胞。通过将聚氨基酸整合到康普茶菌胶团纤维素垫中，可以创建具有高效电荷转移、执行传感转导和进行处理能力的水凝胶生物膜。我们对复合生物膜的忆阻和忆导行为进行了研究，展示了它们执行非传统计算操作的能力。生物膜的多孔纳米结构和电活性创造了一个可用于记录和刺激神经网络的生物相容性界面。除了神经元界面，这些柔软的电活性生物膜还显示出作为生物启发机器人、智能可穿戴设备、非传统计算设备和自适应生物机器人系统组件的潜力。康普茶 - 聚氨基酸复合膜是一种高度可定制的材料，可以根据特定需求进行合成。这些膜属于一类独特的“活”材料，因为它们有能力支持细胞系统并改善生物电子功能。这使它们在各种应用中前景令人兴奋。目前正在持续努力增强在混合生物电子电路中的导电性、信号处理和集成的成分调控。
