Béraneck L, Kaplan G
Rev Rhum Mal Osteoartic. 1985 Jun;52(6):427-30.
Thoracic hyperostosis is a bone disease with an inflammatory appearance which results in hypertrophy and condensation of the bony elements of the anterior thorax, the sternum, the clavicle and the ribs. 14 cases of the primary form of this disease, Köhler's primary sterno-costo-clavicular hyperostosis, have been reported in the literature. This benign disease is associated with only one complication: subclavian vein thrombosis. The secondary forms of thoracic hyperostosis are associated with extrathoracic signs and occur in a context suggestive of spondyloarthropathy. A sub-group is distinguished on the basis of the presence of cutaneous signs: hyperostosis associated with osteoarthritis in the context of palmo-plantar pustulosis (Sonozaki's disease) or severe forms of acne. In the absence of cutaneous signs, thoracic hyperostosis has been exceptionally described in cases of ankylosing spondylitis. It can also be integrated into a more autonomous context, associated with unilateral sacro-iliitis or with vertebral and peripheral osseous condensations. The pathophysiology of thoracic hyperostosis is unknown, but the HLA B27 phenotype does not appear to be involved.
胸段骨质增生是一种具有炎症表现的骨病,可导致前胸、胸骨、锁骨和肋骨的骨质肥大和骨质致密。文献中已报道了14例这种疾病的原发性形式,即科勒原发性胸锁关节骨质增生。这种良性疾病仅伴有一种并发症:锁骨下静脉血栓形成。胸段骨质增生的继发性形式与胸外体征相关,且发生于提示脊柱关节病的背景中。根据皮肤体征的有无可区分出一个亚组:掌跖脓疱病(园崎病)或严重痤疮背景下与骨关节炎相关的骨质增生。在无皮肤体征的情况下,强直性脊柱炎病例中曾有过胸段骨质增生的罕见描述。它也可纳入一个更自主的背景中,与单侧骶髂关节炎或椎体及外周骨质致密相关。胸段骨质增生的病理生理学尚不清楚,但HLA B27表型似乎未参与其中。