队列简介：哥本哈根医院生物样本库-慢性炎症性疾病-炎症性肠病（CHB-CID:IBD）基因队列
Cohort profile: Copenhagen Hospital Biobank-chronic inflammatory disease-inflammatory bowel disease (CHB-CID:IBD) genetic cohort.
作者信息
Darbani Behrooz, Brodersen Thorsten, Liljensøe Anette, Sørensen Signe Bek, Olsson-Svendsen Josephine Bjergbæk, Buil Alfonso, Kamal Ahmed, Schork Andrew J, Poulsen Anja, Kjerulff Bertram Dalskov, Aagaard Bitten, Lund Britta Ørnfelt, Rittig Charlotte Siggaard, Mikkelsen Christina, Larsen Daniel Millencourt, Westergaard David, Rudbeck-Resdal Ditte, Mikkelsen Dorte Helenius, Randers Else, Schiødt Frank Vinholt, Hoffmann Hans Jürgen, Jørgensen Isabella Friis, Brandslund Ivan, Brodersen Jacob Broder, von Stemann Jakob Hjorth, Bay Jakob Thaning, Nissen Janna, Sørensen Jeanette, Boldsen Jens Kjærgaard, Dowsett Joseph, Gladov Josephine, Banasik Karina, Kaspersen Kathrine Agergård, Carlsen Katrine, Dinh Khoa Manh, Kellermann Lauge, Christoffersen Lea Arregui Nordahl, Quinn Liam James Elgaard, Thørner Lise Wegner, Larsen Lone, Aamann Luise, Andersen Malene Rohr, Didriksen Maria, Alexandraki Maria Joanna, Thomsen Marianne Kragh, Julsgaard Mette, Nyegaard Mette, Schwinn Michael, Topholm-Bruun Mie, Leite Mikael Njai, Halling Morten Lee, Pedersen Natalia, Bonderup Ole K, Rohde Palle Duun, Ovesen Pernille Dige, Dessau Ram Benny, Saboori Sanaz, Holm-Christensen Sofie, Bank Steffen, Mikkelsen Susan, Hansen Thomas Folkmann, Werge Thomas, Qvist Niels, Sørensen Erik, Burisch Johan, Hetland Merete Lund, Glintborg Bente, Erikstrup Christian, Brunak Søren, Ullum Henrik, Ostrowski Sisse Rye, Pedersen Ole Birger Vesterager, Andersen Vibeke
机构信息
Molecular Diagnostics and Clinical Research Unit, Department of Internal Medicine, University Hospital of Southern Denmark, Aabenraa, Denmark.
Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark.
出版信息
Eur J Epidemiol. 2025 Jun 9. doi: 10.1007/s10654-025-01239-4.
The Copenhagen Hospital Biobank-chronic inflammatory disease-inflammatory bowel disease (CHB-CID: IBD) cohort contributes to genetic research in inflammatory bowel disease, including Crohn's disease and ulcerative colitis. Of the 327,084 enrolled and genotyped individuals in the cohort, 10,626 have been diagnosed with IBD as of May 2023. The CHB-CID: IBD cohort includes both patients without IBD and healthy blood donors as control groups. Clinical data is collected from Danish registries and patient records, including details on hospital contacts, co-morbidities, medication, surgical procedures, and laboratory investigations. The cohort features a wide age range (> 18 years), extensive population coverage representative of Danish adults, and validated IBD diagnoses. Finally, the cohort benefits from continuous recruitment and regular updates of clinical information. The aim is to enhance IBD management and ultimately improve patients' quality of life.
哥本哈根医院生物样本库-慢性炎症性疾病-炎症性肠病（CHB-CID：IBD）队列有助于炎症性肠病的基因研究，包括克罗恩病和溃疡性结肠炎。在该队列中登记并进行基因分型的327,084名个体中，截至2023年5月，有10,626人被诊断患有IBD。CHB-CID：IBD队列包括未患IBD的患者和健康献血者作为对照组。临床数据从丹麦登记处和患者记录中收集，包括医院接触、合并症、用药、手术程序和实验室检查的详细信息。该队列的特点是年龄范围广（>18岁），广泛覆盖丹麦成年人，IBD诊断经过验证。最后，该队列受益于持续招募和临床信息的定期更新。目的是加强IBD管理并最终改善患者的生活质量。
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