Perspective on acupuncture treatment for diabetic peripheral neuropathy: A perspective.

Acupuncture is increasingly recognized for its potential in managing diabetic peripheral neuropathy (DPN). This condition severely impacts quality of life by inducing symptoms such as pain and sensory loss, and, in severe cases, leading to amputation. Research indicates that acupuncture may alleviate these symptoms through mechanisms that include enhancing neural blood flow, promoting nerve regeneration, and modulating glucose metabolism. Despite these promising findings, the variability in acupuncture's effectiveness, along with the methodological limitations of existing studies-such as small sample sizes and lack of standardization-pose challenges. Future research should therefore focus on conducting large-scale, high-quality trials that could elucidate the specific mechanisms by which acupuncture benefits DPN and confirm its long-term efficacy. This would facilitate acupuncture's integration into comprehensive DPN management strategies, potentially improving outcomes by combining it with pharmacological and other therapies. Optimizing treatment protocols and personalizing acupuncture based on individual patient profiles could further enhance its effectiveness and integration into clinical practice.