Song Joon Young, Kwon Ki Tae, Park Wan Beom, Noh Ji Yun, Park Sun Hee, Choo Eun Ju, Choi Min Joo, Choi Jun Yong, Heo Jung Yeon, Choi Won Suk
Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Division of Infectious Diseases, Department of Internal Medicine, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
Infect Chemother. 2025 Jun;57(2):215-217. doi: 10.3947/ic.2025.0033. Epub 2025 Apr 30.
Annual influenza vaccination is strongly recommended for immunocompromised individuals, who are at a higher risk of severe infection. The Korean Society of Infectious Diseases has revised its influenza vaccination recommendations for solid organ transplant recipients, advocating for the use of highly immunogenic vaccines, such as high-dose inactivated influenza vaccines or MF59-adjuvanted inactivated influenza vaccines, to enhance vaccine efficacy. While further research is needed to extend these recommendations to other immunocompromised populations, these vaccines have demonstrated improved immunogenicity without compromising safety. Expanding vaccination guidelines to additional immunocompromised groups should be considered as more evidence emerges.
强烈建议免疫功能低下的个体每年接种流感疫苗，因为他们发生严重感染的风险更高。韩国传染病学会修订了实体器官移植受者的流感疫苗接种建议，提倡使用高免疫原性疫苗，如高剂量灭活流感疫苗或MF59佐剂灭活流感疫苗，以提高疫苗效力。虽然需要进一步研究将这些建议扩展到其他免疫功能低下人群，但这些疫苗已证明在不影响安全性的情况下免疫原性有所提高。随着更多证据的出现，应考虑将疫苗接种指南扩大到更多免疫功能低下群体。
