Min Eun Jeong, Lee Soo Hyun, Jo Joo-Young, Ahn Jong Gyun, Jeong Dae Chul
Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Division of Medical, Pfizer Biopharmaceuticals Group, Pfizer Pharmaceuticals Korea Limited, Seoul, Korea.
J Korean Med Sci. 2025 Jun 9;40(22):e113. doi: 10.3346/jkms.2025.40.e113.
This study aimed to identify epidemiologic data, including prevalence and incidence, of patients with juvenile idiopathic arthritis (JIA) in accordance with the diseases diagnostic code and Rare Intractable Disease Registration (RIDR) code from the claims data of the Health Insurance Review and Assessment Service (HIRA), the representative secondary data in Korea.
We conducted a retrospective analysis of the national claims data of the HIRA. The study population included 1,728 patients with JIA who 1) had records with diagnostic codes in the format prescribed by the International Classification of Diseases, 10th Revision M08 and the RIDR code V133 between January 1, 2010, and December 31, 2019, and 2) were aged < 16 years as per the definition of JIA. We categorized the patients by age at diagnosis, annual prevalence, and incidence per 100,000 individuals for the study period. Moreover, the study population was stratified by age and gender for subgroup analysis.
The overall prevalence rate for the total, male, and female population was 15.9 (14.5-16.8), 15.4 (13.1-17.0), and 16.4 (15.9-16.9) per 100,000 individuals, respectively. Additionally, the overall incidence rate for the same populations was 2.2 (1.8-2.8), 2.3 (1.7-2.9), and 2.1 (1.8-2.6) per 100,000 individuals, respectively.
To the best of our knowledge, this is the first study presenting the epidemiologic data, including prevalence and incidence, of patients with JIA using population-based claims big data in Korea. The results of this study will aid in understanding the current status of JIA in Korea and Asia and in health care planning.
本研究旨在根据韩国具有代表性的二手数据——健康保险审查与评估服务机构（HIRA）的理赔数据中的疾病诊断代码和罕见难治性疾病登记（RIDR）代码，确定青少年特发性关节炎（JIA）患者的流行病学数据，包括患病率和发病率。
我们对HIRA的全国理赔数据进行了回顾性分析。研究人群包括1728例JIA患者，这些患者满足以下条件：1）在2010年1月1日至2019年12月31日期间有符合《国际疾病分类》第10版M08规定格式的诊断代码记录以及RIDR代码V133；2）根据JIA的定义年龄小于16岁。我们按诊断时的年龄、年患病率以及研究期间每10万人的发病率对患者进行分类。此外，研究人群按年龄和性别分层进行亚组分析。
总体人群、男性人群和女性人群的总体患病率分别为每10万人15.9（14.5 - 16.8）、15.4（13.1 - 17.0）和16.4（15.9 - 16.9）。此外，相同人群的总体发病率分别为每10万人2.2（1.8 - 2.8）、2.3（1.7 - 2.9）和2.1（1.8 - 2.6）。
据我们所知，这是第一项利用韩国基于人群的理赔大数据呈现JIA患者流行病学数据（包括患病率和发病率）的研究。本研究结果将有助于了解韩国和亚洲JIA的现状以及医疗保健规划。
