Penile Abscess Complicating Chronic Penile Calciphylaxis in a Heart Transplant Recipient and End-Stage Renal Disease Patient.

Calciphylaxis, also known as calcific uremic arteriolopathy, is a rare but severe and life-threatening condition that is characterized by cutaneous arteriolar calcification and subsequent tissue necrosis. Calciphylaxis is more commonly seen in patients with end-stage renal disease (ESRD) and has a one-year mortality of greater than 50%. Penile calciphylaxis is extremely rare and carries a high mortality risk. Oftentimes, diagnosis and treatment are challenging. We present a case of a 71-year-old heart transplant recipient and end-stage renal disease patient with a history of chronic penile calciphylaxis who developed penile abscesses, highlighting the challenges of managing this complicated condition.