Misakyan Narine, Abu-Shanab Amer, Shah Shazia
Internal Medicine, Capital Health Medical Center, Trenton, USA.
Internal Medicine, Monmouth Medical Center, Long Branch, USA.
Cureus. 2024 Feb 24;16(2):e54824. doi: 10.7759/cureus.54824. eCollection 2024 Feb.
Penile calciphylaxis is a rare presentation of calcific uremic arteriolopathy and can be a life-threatening condition usually seen in patients with end-stage renal failure with hemodialysis. The clear etiopathogenesis of calciphylaxis is not fully understood, but it is postulated to be characterized by the accumulation of calcium in the microvessels of adipose tissue and skin, which leads to ischemia and necrosis, causing painful ulcerations, and could potentially be complicated by sepsis and mortality. End-stage renal disease (ESRD) is one of the major risk factors for penile calciphylaxis. In this report, we describe a case of a 53-year-old Hispanic male patient with ESRD and diabetes on hemodialysis, who presented with a five-day history of acute, severe, burning, non-radiating pain to the head of his penis associated with black discoloration. He was diagnosed with penile calciphylaxis and received a combination of conservative and surgical interventions, resulting in a highly positive outcome marked by complete healing of the scar without any reported complications.
阴茎钙化防御是钙化性尿毒症小动脉病的一种罕见表现，可能是一种危及生命的疾病，通常见于接受血液透析的终末期肾衰竭患者。钙化防御的确切病因尚未完全明确，但据推测其特征是钙在脂肪组织和皮肤的微血管中积聚，导致缺血和坏死，引起疼痛性溃疡，并可能并发脓毒症和死亡。终末期肾病（ESRD）是阴茎钙化防御的主要危险因素之一。在本报告中，我们描述了一例53岁的西班牙裔男性患者，患有ESRD和糖尿病，正在接受血液透析，他出现了阴茎头部急性、剧烈、灼痛、无放射痛且伴有黑色变色的五天病史。他被诊断为阴茎钙化防御，并接受了保守和手术相结合的干预措施，结果非常理想，瘢痕完全愈合，未报告任何并发症。
