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阴茎钙化防御:一例采用部分阴茎切除术治疗的严重病例。

Penile calciphylaxis: A severe case managed with partial penectomy.

作者信息

Adler Kerry, Flores Viktor, Kabarriti Abdo

机构信息

State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY, 11203, USA.

出版信息

Urol Case Rep. 2020 Oct 16;34:101456. doi: 10.1016/j.eucr.2020.101456. eCollection 2021 Jan.

DOI:10.1016/j.eucr.2020.101456
PMID:33102133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7578200/
Abstract

Penile calciphylaxis, a rare manifestation of calcific uremic arteriolopathy, is infrequently reported in the literature. Surgical management has demonstrated similar outcomes as conservative management in terms of mean survival time. Therefore, the benefits of surgical intervention for this disease remain controversial. In this report, we present a case of penile calciphylaxis in a hemodialysis-dependent patient with end stage renal disease (ESRD). The interest of this case lies in the severity of illness on initial presentation, which precluded the possibility of conservative management and necessitated penectomy as a means of halting disease progression and improving patient quality of life.

摘要

阴茎钙化防御是钙性尿毒症小动脉病的一种罕见表现,文献中鲜有报道。在平均生存时间方面,手术治疗与保守治疗的效果相似。因此,针对这种疾病进行手术干预的益处仍存在争议。在本报告中,我们呈现了一例终末期肾病(ESRD)且依赖血液透析的患者发生阴茎钙化防御的病例。该病例的关注点在于初次就诊时病情的严重程度,这使得保守治疗不可能实现,因而有必要进行阴茎切除以阻止疾病进展并改善患者生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ead/7578200/6e6065341941/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ead/7578200/1c7f2db5d9fe/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ead/7578200/6e6065341941/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ead/7578200/1c7f2db5d9fe/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ead/7578200/6e6065341941/gr2.jpg

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本文引用的文献

1
Penile calciphylaxis: A retrospective case-control study.阴茎钙化性栓塞症:一项回顾性病例对照研究。
J Am Acad Dermatol. 2021 Nov;85(5):1209-1217. doi: 10.1016/j.jaad.2020.05.042. Epub 2020 May 15.
2
Penile gangrene due to calciphylaxis: a multidisciplinary approach to a complex clinical challenge.钙化防御所致阴茎坏疽:应对复杂临床挑战的多学科方法
BMJ Case Rep. 2019 Dec 5;12(12):e232138. doi: 10.1136/bcr-2019-232138.
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Calcific uraemic arteriolopathy: an update.钙化性尿毒症小动脉病:最新进展
Cureus. 2024 Feb 24;16(2):e54824. doi: 10.7759/cureus.54824. eCollection 2024 Feb.
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Risk factors, treatment modalities, and clinical outcomes of penile calciphylaxis: systematic review.阴茎钙化性血管病的风险因素、治疗方式和临床结局:系统综述。
World J Urol. 2023 Nov;41(11):2959-2966. doi: 10.1007/s00345-023-04611-9. Epub 2023 Oct 2.
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Penile calciphylaxis in a patient with concurrent haemodialysis and Coumadin treatment.并发血液透析和华法林治疗的患者发生阴茎钙化防御。
BMJ Case Rep. 2023 May 2;16(5):e254925. doi: 10.1136/bcr-2023-254925.
6
Penile calciphylaxis in a patient with end-stage renal disease and chronic hemodialysis: a case report.终末期肾病并慢性血液透析患者阴茎钙化防御:病例报告。
Pan Afr Med J. 2022 Nov 14;43:136. doi: 10.11604/pamj.2022.43.136.37673. eCollection 2022.
7
Perioperative Management of Calciphylaxis: Literature Review and Treatment Recommendations.钙化防御的围手术期管理:文献综述与治疗建议
Orthop Rev (Pavia). 2022 Aug 25;14(3):37573. doi: 10.52965/001c.37573. eCollection 2022.
8
Penile calciphylaxis-a complicated case managed with circumcision and glansectomy.阴茎钙化防御——一例通过包皮环切术和龟头切除术治疗的复杂病例。
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9
Effect of all-in-one nursing model on ICU ventilator-associated pneumonia.一体化护理模式对重症监护病房呼吸机相关性肺炎的影响。
Am J Transl Res. 2021 May 15;13(5):5080-5086. eCollection 2021.
Curr Opin Nephrol Hypertens. 2008 Nov;17(6):629-34. doi: 10.1097/MNH.0b013e32830f4566.
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Penile calciphylaxis: analysis of risk factors and mortality.阴茎钙化防御:危险因素及死亡率分析
J Urol. 2003 Jun;169(6):2206-9. doi: 10.1097/01.ju.0000064334.85656.a1.
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Calciphylaxis in chronic renal failure.慢性肾衰竭中的钙过敏症
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