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阿富汗的脊柱结核:2019 - 2020年喀布尔医院患者研究

Spinal tuberculosis in Afghanistan: A 2019-2020 study of patients in Kabul hospitals.

作者信息

Qaderi Farah, Mashid Idriss, Gachkar Latif, Martellucci Mosè, Qaderi Shohra, Ozaki Akihiko, Haghbin Toutounchi Alireza, Taheriazam Afshin, Asakura Takanori, Gholipoor Talemi Hojat, Mohammady Noria, Shabani Minoosh

机构信息

School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.

Department of Medicine Kabul University of Medical Sciences Kabul Afghanistan.

出版信息

Public Health Chall. 2023 Sep 30;2(4):e120. doi: 10.1002/puh2.120. eCollection 2023 Dec.

Abstract

BACKGROUND

Tuberculosis (TB) is endemic in many low-income countries, which can affect the spine in 1%-5% of those with an active infection. This study reports the clinical characteristics of patients admitted for spinal TB in Kabul, Afghanistan, a country with very limited resources.

METHODS

This was a descriptive study among 26 patients treated for spinal TB in three major referral hospitals in Kabul, Afghanistan, between March 2019 and April 2020. The sociodemographic and clinical details, gender, age, site of infection, presenting complaints, signs, and symptoms of the patients were retrieved from their medical records. Summary statistics were analyzed using SPSS version 20. Ethics approval was obtained from the ethics committee of Shahid Beheshti University of Medical Sciences in Tehran, Iran.

RESULTS

Data were available for 26 patients with spinal TB admitted consecutively. The mean age of the sample was 38.2 years (SD 17.5), and there were 16 males and 10 females. Median time from symptom onset to hospital admission was 60 days. The most common diagnostic imaging technique used was magnetic resonance imaging (92.3%), followed by computed tomography (7.7%). The majority of the lesions involved the lumbar spine (61.4%), followed by the thoracolumbar spine (30.8%). Back pain was the most common manifestation in 21 patients (80.8%), and varying degrees of neurological impairment were found in 16 (61.5%) patients. There were no deaths among the patients up to the discharge date.

CONCLUSIONS

This study describes the clinical characteristics of spinal TB among patients in Kabul, Afghanistan. It is essential to strengthen preventive strategies and to improve health awareness about clinical features of spinal TB in patients with chronic back pain even in the absence of signs of TB.

摘要

背景

结核病在许多低收入国家呈地方性流行,活动性感染患者中1%-5%的人脊柱会受到影响。本研究报告了阿富汗喀布尔脊柱结核患者的临床特征,该国资源非常有限。

方法

这是一项描述性研究,对2019年3月至2020年4月期间在阿富汗喀布尔三家主要转诊医院接受脊柱结核治疗的26例患者进行了研究。从他们的病历中获取患者的社会人口统计学和临床细节、性别、年龄、感染部位、主诉、体征和症状。使用SPSS 20版进行汇总统计分析。获得了伊朗德黑兰沙希德·贝赫什提医科大学伦理委员会的伦理批准。

结果

连续收治的26例脊柱结核患者的数据可用。样本的平均年龄为38.2岁(标准差17.5),男性16例,女性10例。从症状出现到入院的中位时间为60天。最常用的诊断成像技术是磁共振成像(92.3%),其次是计算机断层扫描(7.7%)。大多数病变累及腰椎(61.4%),其次是胸腰椎(30.8%)。背痛是21例患者(80.8%)最常见的表现,16例(61.5%)患者有不同程度的神经功能损害。截至出院日期,患者中无死亡病例。

结论

本研究描述了阿富汗喀布尔患者脊柱结核的临床特征。即使在没有结核病迹象的情况下,加强预防策略并提高慢性背痛患者对脊柱结核临床特征的健康意识也至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9202/12039708/1c838d8b8125/PUH2-2-e120-g003.jpg

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