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狮子肉毒中毒的诊断与治疗

Diagnosis and treatment of botulism in lions.

作者信息

Greenwood A G

出版信息

Vet Rec. 1985 Jul 20;117(3):58-60. doi: 10.1136/vr.117.3.58.

DOI:10.1136/vr.117.3.58
PMID:4049682
Abstract

Six circus lions (Panthera leo) showed neurological and gastrointestinal signs after consuming casualty broiler chickens. Signs included ataxia, hindlimb paralysis and recumbency. Neurological examination of two affected males showed paralysis of extraocular muscles, fixed dilated pupils and inability to swallow. Replacement fluids and antibiotics were given and Clostridium botulinum type C antitoxin was found in serum samples. Type C antitoxin was not then available and therapy was started in one lioness with guanidine hydrochloride. Convulsions were controlled by diazepam but this animal died. One of the two males was given type C antitoxin; both were given anabolic steroids. All the remaining animals made slow recoveries over varying periods; one lion was recumbent for 41 days. No lion developed respiratory paralysis; other animals which had consumed the chickens remained healthy. Aspects of the treatment of botulism in animals are discussed.

摘要

六只马戏团狮子( Panthera leo)在食用了病死肉鸡后出现神经和胃肠道症状。症状包括共济失调、后肢麻痹和卧地不起。对两只患病雄性狮子的神经检查显示眼外肌麻痹、瞳孔固定散大且无法吞咽。给予了补液和抗生素治疗,血清样本中检测到了C型肉毒杆菌抗毒素。当时没有C型抗毒素,于是对一只母狮开始用盐酸胍进行治疗。惊厥用安定控制,但这只动物死亡。两只雄性狮子中的一只给予了C型抗毒素;两只都给予了合成代谢类固醇。其余所有动物在不同时期缓慢康复;一只狮子卧地不起达41天。没有狮子出现呼吸麻痹;食用了这些鸡的其他动物保持健康。文中讨论了动物肉毒中毒的治疗方面。

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Natural Clostridium botulinum type C toxicosis in a group of cats.一组猫的自然型C型肉毒梭菌中毒
J Clin Microbiol. 2004 Nov;42(11):5406-8. doi: 10.1128/JCM.42.11.5406-5408.2004.
2
A comparison of human and animal botulism: a review.人类与动物肉毒中毒的比较:综述
J R Soc Med. 1991 May;84(5):295-8. doi: 10.1177/014107689108400516.