Critchley E M
Department of Neurology, Royal Preston Hospital.
J R Soc Med. 1991 May;84(5):295-8. doi: 10.1177/014107689108400516.
Botulism can arise from preformed toxin, wound infection or intestinal toxico-infection. All three forms can occur in humans as well as in animals. The examination of botulism in veterinary practice can alert the medical profession to the hazards which can occur with the introduction of dietary alterations and hermetic sealing of foodstuffs. There is also the possibility that the development of pica through lack of essential nutrients could lead to the ingestion of contaminated substances rendering the child (or even adult) susceptible to botulinum intoxication. A positive gain has been that research leading to the elimination of shaker foal disease has provided a comprehensive analysis of factors which may underline the risk of toxico-infection in infants.
肉毒中毒可由预先形成的毒素、伤口感染或肠道毒血症感染引起。这三种形式在人类和动物中都可能发生。兽医实践中对肉毒中毒的检查可以提醒医学界注意饮食改变和食品密封可能带来的危害。此外,由于缺乏必需营养素而导致异食癖的发展,可能会使儿童(甚至成人)摄入受污染物质,从而易患肉毒杆菌中毒。一个积极的成果是,导致消除摇晃驹病的研究对可能构成婴儿毒血症感染风险的因素进行了全面分析。