Pham Ai H T, Ha Thao H, Le Thanh Q, Nguyen Dat Q, Vo Tuan M
Department of General Gynaecology, TuDu Hospital, Ho Chi Minh City, Vietnam.
Department of Obstetrics and Gynecology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Int J Womens Health. 2025 Jun 5;17:1673-1679. doi: 10.2147/IJWH.S519586. eCollection 2025.
HPV infection is a major contributor to cervical cancer, a common type of cancer affecting Vietnamese women. To develop effective prevention strategies for cervical cancer, it is crucial to understand the prevalence of high-risk HPV infection in communities. The objectives of this study were to determine the prevalence and distribution of HPV types among female residents in Ho Chi Minh City.
This cross-sectional study employed a self-collection method, involving 775 participants selected using a Probability Proportional to Size technique (PPS) between January and December 2024.
The study found that 7.5% [95% CI: 5.6-9.3] of the 775 specimens tested positive for high-risk HPV infection, with HPV-16 accounting for 9.7%, HPV-18 for 3.2%, and other high-risk types for 87.1% (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 và 68). Compared to similar studies many years ago in Vietnam, the prevalence of high-risk HPV infection has not changed much. However, among high-risk HPV infections, the ratio of types 16 and 18 has decreased dramatically.
Findings from this investigation reveal that the high-risk HPV infection prevalence in Ho Chi Minh City communities is consistent with earlier research. Nevertheless, a significant change has been observed in the distribution of high-risk HPV genotypes. Specifically, the proportional representation of HPV types 16 and 18 within the high-risk HPV infection group has substantially diminished, now representing only approximately 30% of their prevalence a decade prior.
人乳头瘤病毒（HPV）感染是宫颈癌的主要致病因素，宫颈癌是影响越南女性的一种常见癌症。为制定有效的宫颈癌预防策略，了解社区中高危HPV感染的流行情况至关重要。本研究的目的是确定胡志明市女性居民中HPV类型的流行率和分布情况。
本横断面研究采用自我采集方法，于2024年1月至12月期间，通过规模比例概率抽样技术（PPS）选取了775名参与者。
研究发现，在检测的775份样本中，7.5%[95%置信区间：5.6 - 9.3]的样本高危HPV感染呈阳性，其中HPV - 16占9.7%，HPV - 18占3.2%，其他高危类型占87.1%（31、33、35、39、45、51、52、56、58、59、66和68型）。与越南多年前的类似研究相比，高危HPV感染的流行率变化不大。然而，在高危HPV感染中，16型和18型的比例显著下降。
本次调查结果显示，胡志明市社区高危HPV感染的流行率与早期研究一致。然而，高危HPV基因型的分布出现了显著变化。具体而言，高危HPV感染组中HPV 16型和18型的比例大幅下降，目前仅约为十年前流行率的30%。
