Olivieri Federico, Orlo Elena, Spinelli Elodia, Castaldo Rachele, Gentile Gennaro, Licoccia Silvia, Lavorgna Margherita, Lavorgna Marino
Institute of Polymers Composites and Biomaterials, National Research Council of Italy, 80078 Pozzuoli, Italy.
Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.
Nanomaterials (Basel). 2025 Jun 4;15(11):866. doi: 10.3390/nano15110866.
Mesoporous silica nanoparticles (MSNs) functionalized with silane quaternary ammonium compounds (SiQACs) were synthesized and utilized as carriers for thymus essential oil (TO), a green bio-antifouling agent. The synthesis of MSNs functionalized with SiQACs was carried out in a single step, with clear advantages in terms of simplicity of the process, high yield (94%) and saving of reagents and solvents for the MSN purification. After loading with TO, this innovative dual-action antifouling system was able to integrate the intrinsic biocidal properties of SiQACs with the release of TO from MSN pores, resulting in an engineered material with prolonged efficacy. The antifouling compounds incorporated into the nanoparticles accounted for 42% of the total weight. The biocidal performance was evaluated by monitoring the growth inhibition of , a microalga commonly associated with stone biodeterioration. Additionally, these nanoparticles were embedded in a commercial silane-based protective coating and applied to tuff stone samples to assess their ability to mitigate biofilm formation over extended periods. Results demonstrated the system's high potential for durable protection against microbial colonization and biofilm growth on stone surfaces.
合成了用硅烷季铵化合物（SiQACs）功能化的介孔二氧化硅纳米颗粒（MSNs），并将其用作绿色生物防污剂胸腺精油（TO）的载体。用SiQACs功能化的MSNs的合成一步完成，在工艺简单性、高收率（94%）以及节省MSN纯化所需的试剂和溶剂方面具有明显优势。负载TO后，这种创新的双效防污系统能够将SiQACs的固有杀菌特性与TO从MSN孔中的释放相结合，从而产生一种具有长效功效的工程材料。纳入纳米颗粒的防污化合物占总重量的42%。通过监测一种通常与石材生物劣化相关的微藻的生长抑制来评估杀菌性能。此外，将这些纳米颗粒嵌入商业硅烷基保护涂层中，并应用于凝灰岩样品，以评估它们在较长时间内减轻生物膜形成的能力。结果表明，该系统在持久保护石材表面免受微生物定殖和生物膜生长方面具有很高的潜力。
