Jacobson J A, Nichols C R, Kasworm E M
West J Med. 1985 Sep;143(3):337-41.
The sustained high incidence of staphylococcal toxic shock syndrome (TSS) in Utah provided an opportunity to examine changes in the epidemiology of this disease during a period of greater media attention to the syndrome and increased scientific understanding of its etiology and pathogenesis. An apparent peak in the statewide incidence of TSS in 1980 appears in part attributable to self-reporting of outpatient cases. The incidence of the syndrome in patients having a nasal operation appears equal to or greater than the incidence in menstrual-age women. The case-fatality ratio and recurrence rate of TSS have declined since widespread recognition of the syndrome, possibly related to earlier diagnosis and initiation of antistaphylococcal therapy. Identifying milder cases has also contributed to a lower mortality.
犹他州葡萄球菌中毒性休克综合征(TSS)持续高发,这为研究在媒体对该综合征关注度更高、对其病因和发病机制的科学认识增加的时期内,这种疾病的流行病学变化提供了契机。1980年全州TSS发病率明显出现峰值,部分原因是门诊病例的自我报告。接受鼻部手术患者中该综合征的发病率似乎等于或高于育龄期女性中的发病率。自该综合征被广泛认识以来,TSS的病死率和复发率有所下降,这可能与早期诊断和开始抗葡萄球菌治疗有关。识别病情较轻的病例也有助于降低死亡率。