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[1980 - 1983年维也纳地区沙门氏菌耐药性的发展]

[Development of Salmonella resistance in the Vienna area 1980-1983].

作者信息

Stur D, Presslich J

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A. 1985 Jul;259(4):564-71.

PMID:4050201
Abstract

During 1982-83 the frequency of single chemoresistant Salmonella isolates declined compared with the period of 1980-81. This decrease is evident regardless of whether the material is grouped according to serovars or to regions. However, the degree of resistance in multiresistant isolates increased. The frequency of S. saint-paul decreased, but continued to have the highest degree of resistance. In the D1 group there were almost exclusively mono-resistant isolates. 59% of all resistant isolates were resistant to tetracyclin, 47% to streptomycine and 25% to sulfonamides. Sensitive isolates predominate in outbreaks, except for one outbreak of S. enteritidis, which showed a marked percentage of bacteria with reduced sensibility against cephalosporine. The resistance patterns showed considerable variance over the time of observation. All types of resistance appeared much more frequently than expected from calculation of possible gene-bound properties; the only exception was the double resistance to cephalosporine and tetracycline which corresponds with genetic laws.

摘要

在1982 - 1983年期间,与1980 - 1981年相比,单一化学耐药性沙门氏菌分离株的频率有所下降。无论材料是按血清型还是按地区分组,这种下降都是明显的。然而,多重耐药分离株的耐药程度有所增加。圣保罗沙门氏菌的频率下降,但仍具有最高的耐药程度。在D1组中几乎全是单一耐药分离株。所有耐药分离株中,59%对四环素耐药,47%对链霉素耐药,25%对磺胺类药物耐药。除了一次肠炎沙门氏菌爆发外,敏感分离株在疫情爆发中占主导地位,该次爆发显示出对头孢菌素敏感性降低的细菌比例显著。在观察期间,耐药模式显示出相当大的差异。所有类型的耐药出现的频率都比根据可能的基因结合特性计算预期的要高得多;唯一的例外是对头孢菌素和四环素的双重耐药,这符合遗传规律。

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