Korsun' I V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(8):1192-200.
A clinico-genealogic study of 66 patients with neurosis-like schizophrenia showed a certain genetic heterogeneity of schizophrenia with obsessions. In cases of an unfavourable course of the schizophrenic process in a proband (a malignant disease of obsessions), the familial background was largely determined by disturbances of the schizophrenic spectrum. In cases of a slow progression of the disease (slowly progressive pseudoneurotic schizophrenia), the hereditary background was characterized by a great variability of psychopathological manifestations. Along with schizophrenia-related abnormalities, the families of such patients featured the accumulation of constitutional anomalies, neurotic disturbances and subclinical affective disorders.
一项对66例类神经症型精神分裂症患者的临床谱系研究表明，伴有强迫观念的精神分裂症存在一定的遗传异质性。在先证者（强迫观念的恶性疾病）精神分裂症病程不利的情况下，家族背景很大程度上由精神分裂症谱系障碍决定。在疾病进展缓慢的情况下（缓慢进展的假神经症型精神分裂症），遗传背景的特征是精神病理表现具有很大的变异性。除了与精神分裂症相关的异常外，这类患者的家族还表现出体质异常、神经症性障碍和亚临床情感障碍的累积。
