Ahn Ji Yong
Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Korean J Helicobacter Up Gastrointest Res. 2024 Sep;24(3):238-242. doi: 10.7704/kjhugr.2024.0031. Epub 2024 Sep 9.
infection has been associated with various gastric diseases, including ulcers, adenomas, and adenocarcinomas. Over 40 years since the discovery of , numerous studies have shown that eradication therapy can help prevent gastric cancer not only in healthy individuals but also in patients who have already been treated for early gastric cancer. Moreover, some studies have shown that eradication therapy can improve gastric mucosal inflammatory diseases, such as atrophic changes and intestinal metaplasia. This article reviews the epidemiology of infections and gastric cancer, mechanisms of -associated gastric cancer development, and current evidence supporting the benefits of eradication for reducing or preventing gastric cancer.
感染与多种胃部疾病相关,包括溃疡、腺瘤和腺癌。自发现[具体病原体]以来的40多年里,众多研究表明,根除[具体病原体]疗法不仅有助于预防健康个体患胃癌,对于已接受早期胃癌治疗的患者也有同样效果。此外,一些研究表明,根除[具体病原体]疗法可改善胃黏膜炎症性疾病,如萎缩性改变和肠化生。本文综述了[具体病原体]感染与胃癌的流行病学、[具体病原体]相关胃癌的发病机制,以及目前支持根除[具体病原体]对降低或预防胃癌有益的证据。