Fanget Marie, Labeix Pierre, Morin Jean-Benoit, Bayle Manon, Koral Jerome, Testa Rodolphe, Peyrot Nicolas, Gremeaux Vincent, Iliou Marie-Christine, Busso Thierry, Laukkanen Jari Antero, Roche Frederic, Hupin David
Department of Clinical and Exercise Physiology, University of Jean Monnet, University Hospital of Saint-Etienne, Mines Saint-Etienne, INSERM, U 1059, Saint-Etienne, Saint-Priest-en-Jarez 42270, France.
Inter-university Laboratory of Human Movement Biology, EA 7424, UJM-Saint-Etienne, Saint-Priest-en-Jarez 42270, France.
Eur Heart J Open. 2025 Apr 22;5(3):oeaf036. doi: 10.1093/ehjopen/oeaf036. eCollection 2025 May.
Individually optimizing the training programme of cardiac rehabilitation (CR) remains a major concern among coronary artery disease (CAD) patients. The power-force-velocity profile (PFVP) for a given task is usually assessed to improve performance in athletes through individualized training. Therefore, assessing PFVP on stationary cycle ergometer may allow better personalization of CR programme. The aim of this study was to compare the effects of a new CR customized based on patient's PFVP vs. a traditional CR in CAD patients on cardiorespiratory, biological, and muscular systems.
A total of 86 patients participated in this study. The 3-week intervention consisted of physical training sessions (4/week) and therapeutic education workshops (1/week). Experimental group patients followed a specific cycle ergometer training programme focusing on their less developed PFVP quality. Control patients attended a conventional CR programme. Cardiopulmonary exercise test (VO at the first ventilatory threshold, VT, and the peak), blood tests [LDL and HDL cholesterol (LDL-C and HDL-C)], and handgrip and quadriceps force were assessed at baseline and after CR. The mean age was 60.8 ± 9.6 years, and 15% were women. A significantly greater benefit in VO (experimental: +21.5 ± 19.2% vs. control: +10.5 ± 15.8%, < 0.001), VO at VT (experimental: +35.5 ± 33.6% vs. control: +8.4 ± 31.2%, < 0.001), and LDL-C ( = 0.001) were observed in the experimental group. Both groups significantly increased HDL-C and muscle parameters.
The novel CR, based on initial individual PFVP performed on stationary cycle ergometer, showed greater benefits on cardiorespiratory capacities and lipid profile than a conventional, non-individualized CR. Therefore, PFVP could be used in CR to adapt specifically the content of training sessions.
针对冠心病（CAD）患者，如何单独优化心脏康复（CR）训练方案仍是一个主要问题。通常会评估给定任务的功率-力量-速度曲线（PFVP），以便通过个性化训练提高运动员的表现。因此，在固定自行车测力计上评估PFVP可能会使CR方案的个性化程度更高。本研究的目的是比较基于患者PFVP定制的新型CR与传统CR对CAD患者心肺、生物和肌肉系统的影响。
共有86名患者参与本研究。为期3周的干预包括体育训练课程（每周4次）和治疗教育工作坊（每周1次）。实验组患者遵循特定的自行车测力计训练方案，重点关注其发育较差的PFVP质量。对照组患者参加传统的CR方案。在基线和CR后评估心肺运动试验（第一通气阈值、VT时的VO以及峰值）、血液检查[低密度脂蛋白和高密度脂蛋白胆固醇（LDL-C和HDL-C）]以及握力和股四头肌力量。平均年龄为60.8±9.6岁，女性占15%。实验组在VO（实验组：+21.5±19.2% vs.对照组：+10.5±15.8%，P<0.001）、VT时的VO（实验组：+35.5±33.6% vs.对照组：+8.4±31.2%，P<0.001）和LDL-C（P = 0.001）方面观察到显著更大的益处。两组的HDL-C和肌肉参数均显著增加。
基于在固定自行车测力计上进行的初始个体PFVP的新型CR，在心肺功能和血脂谱方面比传统的非个性化CR显示出更大的益处。因此，PFVP可用于CR中，以专门调整训练课程的内容。
