Moon Hee Seok
Korean J Helicobacter Up Gastrointest Res. 2023 Mar;23(1):22-27. doi: 10.7704/kjhugr.2023.0019. Epub 2023 Mar 9.
() is a well-known gastrointestinal microorganism that causes chronic gastritis and peptic ulcers, which may evolve into gastric cancer. Previous studies have shown that eradication inhibits the development of primary and metachronous gastric cancer. Therefore, the Kyoto global consensus recommends eradication therapy for both symptomatic and asymptomatic -infected patients. Gastric cancer is detected even in patients after successful eradication. Recent studies have reported the role of endoscopy in detection of primary gastric cancers after eradication. Development of gastric cancer may be observed several months or even >10 years after successful eradication. Therefore, identification of high-risk patients in whom extensive surveillance may prove beneficial represents a clinical dilemma. In this review, the characteristics of gastric cancer patients who have undergone successful -eradication therapy are summarized.
(幽门螺杆菌)是一种引起慢性胃炎和消化性溃疡的知名胃肠道微生物,这些疾病可能会发展为胃癌。先前的研究表明,根除幽门螺杆菌可抑制原发性和异时性胃癌的发展。因此,京都全球共识建议对有症状和无症状的幽门螺杆菌感染患者进行根除治疗。即使在成功根除幽门螺杆菌的患者中也能检测到胃癌。最近的研究报道了内镜检查在根除幽门螺杆菌后原发性胃癌检测中的作用。在成功根除幽门螺杆菌数月甚至超过10年后,仍可能观察到胃癌的发生。因此,识别可能从广泛监测中获益的高危患者是一个临床难题。在这篇综述中,总结了成功接受幽门螺杆菌根除治疗的胃癌患者的特征。