Moore Bradley S, Newman David J
Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California 92093-0204, United States.
Skaggs School of Pharmacy and Pharmaceutical Sciences, 92093-0204, La Jolla, California 92093-0204, United States.
J Nat Prod. 2025 Jun 27;88(6):1541-1548. doi: 10.1021/acs.jnatprod.5c00554. Epub 2025 Jun 12.
The connection between humans and Nature's chemistry is astonishing and built into the very fabric of our genetic code. In this Perspective, we focus on bioactive molecules from microbes, plants, and animals that transformed our health and society and continue to change the course of human history. In light of our changing planet and recent public distrust in science, our intimate connection with Nature and its solutions to our problems are in peril. It has never been more important to invest new effort into understanding the mysteries of life's molecules to preserve our own existence.
人类与大自然的化学之间的联系令人惊叹,并且深深嵌入我们遗传密码的结构之中。在这篇视角文章中,我们聚焦于来自微生物、植物和动物的生物活性分子,这些分子改变了我们的健康和社会,并持续影响着人类历史的进程。鉴于我们不断变化的星球以及近期公众对科学的不信任,我们与大自然的紧密联系以及大自然为我们问题提供的解决方案正处于危险之中。投入新的努力去理解生命分子的奥秘以维护我们自身的生存,从未像现在这样重要。