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人类胎儿器官中的储存铁。

Storage iron in human foetal organs.

作者信息

Singla P N, Gupta V K, Agarwal K N

出版信息

Acta Paediatr Scand. 1985 Sep;74(5):701-6. doi: 10.1111/j.1651-2227.1985.tb10017.x.

DOI:10.1111/j.1651-2227.1985.tb10017.x
PMID:4050416
Abstract

Maternal plasma iron and storage iron (non-heme) in the foetal liver were estimated in 108 foetuses whose gestational ages ranged from 12-44 weeks. Simultaneous estimations of storage iron were also made on the spleen and kidney in 70 and 69 of these foetuses respectively. Although the concentration of iron per g wet tissue in these organs remained practically the same at all gestations, the total storage iron content increased with the increase in gestation due to growth of these organs. The liver, in particular, showed a steep rise in total iron content in the last 8 weeks of gestation. There was a significant positive correlation between the total storage iron content in the foetal organs and the birth weight and gestational age of the foetus, suggesting that the preterm infants had smaller iron stores at birth as compared to infants born at term. The direct relation of the concentration as well as the total content of storage iron in the foetal liver with the maternal plasma iron levels suggested that babies born to iron deficient mothers had poor iron stores in their livers.

摘要

对108例胎龄在12至44周之间的胎儿的母体血浆铁和胎儿肝脏中的储存铁(非血红素铁)进行了估算。同时,分别对其中70例和69例胎儿的脾脏和肾脏进行了储存铁的估算。尽管这些器官中每克湿组织的铁浓度在所有孕期基本保持不变,但由于这些器官的生长,储存铁的总含量随着孕期的增加而增加。特别是肝脏,在妊娠的最后8周总铁含量急剧上升。胎儿器官中储存铁的总含量与胎儿出生体重和胎龄之间存在显著正相关,这表明与足月儿相比,早产儿出生时的铁储备较少。胎儿肝脏中储存铁的浓度和总含量与母体血浆铁水平的直接关系表明,缺铁母亲所生的婴儿肝脏中铁储备不足。

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