Marcus Valentina B, Bertonha Igor B, Eisenhardt Luiza M, Kommers Glaucia D, Flores Mariana M
Programa de Pós-Graduação em Medicina Veterinária, Centro de Ciências Rurais, Universidade Federal de Santa Maria, 1000 Roraima Av., Santa Maria, RS, 97105-900, Brazil.
Curso de Graduação em Medicina Veterinária, Centro de Ciências Rurais, Universidade Federal de Santa Maria, 1000 Roraima Av., Santa Maria, RS, 97105-900, Brazil.
J Comp Pathol. 2025 Jul;220:23-29. doi: 10.1016/j.jcpa.2025.05.005. Epub 2025 Jun 11.
Nasal cavity exploration is not a part of conventional necropsy, and systematic studies analysing histopathological changes in the upper respiratory tract of asymptomatic cats and dogs are scarce. This prospective study was carried out to evaluate the nasal cavity of all dogs and cats submitted to necropsy in a Brazilian veterinary anatomic pathology service from January to December 2023. Of 81 animals included (54 dogs and 27 cats), 67 (82.7 %) had one or more histological changes in the nasal cavity. Idiopathic lymphoplasmacytic rhinitis was the most common change in both species (45/67 [67.2 %]) and one dog with severe inflammation had secondary nasal conchae atrophy. In dogs, erosions and ulcers were the second most prevalent change (4/48 [8.3 %]), and two of these were secondary to uraemia. Oronasal fistulae were seen in two dogs (2/48 [4.2 %]). Neutrophilic rhinitis was the second most prevalent change in cats (5/19 [26.3 %]), one case being associated with Candida sp infection. Neoplastic changes were infrequent in both species (5/67 [7.4 %]). Systematically analysing the histological appearance of the nasal mucosa in presumably asymptomatic animals helps enlighten clinicians and pathologists on what to expect in nasal biopsy samples, assisting them in interpretation of the clinical significance of different lesions and improving the diagnosis of nasal cavity conditions of dogs and cats.
鼻腔探查并非传统尸检的一部分，且缺乏对无症状猫和犬上呼吸道组织病理学变化进行分析的系统性研究。本前瞻性研究旨在评估2023年1月至12月在巴西一家兽医解剖病理学服务机构接受尸检的所有犬猫的鼻腔。在纳入的81只动物（54只犬和27只猫）中，67只（82.7%）鼻腔有一处或多处组织学变化。特发性淋巴细胞浆细胞性鼻炎是两个物种中最常见的变化（45/67 [67.2%]），一只患有严重炎症的犬继发鼻甲萎缩。在犬中，糜烂和溃疡是第二常见的变化（4/48 [8.3%]），其中两例继发于尿毒症性。两只犬出现口鼻瘘（2/48 [4.2%]）。嗜中性粒细胞性鼻炎是猫中第二常见的变化（5/19 [26.3%]），1例与念珠菌属感染有关。两个物种中的肿瘤性变化均不常见（5/67 [7.4%]）。系统分析疑似无症状动物鼻腔黏膜的组织学表现有助于让临床医生和病理学家了解鼻腔活检样本中可能出现的情况，协助他们解读不同病变的临床意义，并改善犬猫鼻腔疾病的诊断。
