Matsumoto J, Yamasaki Y, Katoh M, Tada S
Hinyokika Kiyo. 1985 May;31(5):895-900.
Cinoxacin was administered to 30 outpatients with chronic complicated urinary tract infection for 57.3 days (average) and the following results were obtained. Clinical efficacy based on decrease of pyuria were "excellent" in 44.8%, "good" in 31.0%, "fair" in 24.1%, and "poor" in 0%; and, overall effectiveness rate reached 75.9%. As for side effect, diarrhea and nausea were observed in 2 and 1 patients, respectively. GOT and GPT elevation was also seen in one case. Cinoxacin long term therapy seems to be effective and useful to chronic complicated urinary tract infections.
环丙沙星用于30例慢性复杂性尿路感染门诊患者,疗程平均为57.3天,获得了以下结果。基于脓尿减少的临床疗效为:“优”占44.8%,“良”占31.0%,“中”占24.1%,“差”占0%;总有效率达75.9%。副作用方面,分别有2例和1例患者出现腹泻和恶心。还有1例出现谷草转氨酶和谷丙转氨酶升高。环丙沙星长期治疗似乎对慢性复杂性尿路感染有效且实用。