Ueyama H
Hinyokika Kiyo. 1984 Jun;30(6):849-55.
Twenty-two patients with chronic complicated urinary tract infections were treated with 400 to 1,200 mg/day cinoxacin for 2 to 12 months. Assessment of drug efficacy was based on monthly urinalysis. Clinical response rates were "excellent" in 32.3%, "good" in 27.9%, and "poor" in 39.8% of the participants. Overall effective rate reached 60.2%. No cases of side-effects or toxicity were seen. Long-term cinoxacin therapy is both safe and effective in the treatment of chronic complicated urinary tract infections.