Uyar Galip Can
Department of Medical Oncology, Ankara Etlik City Hospital, Ankara, Turkey.
Support Care Cancer. 2025 Jun 13;33(7):572. doi: 10.1007/s00520-025-09628-x.
Chemotherapy-induced taste alterations are a prevalent but frequently under-recognized complication with significant nutritional and psychosocial consequences. In this letter, we offer a critical appraisal of the recent study by Köksal et al., highlighting key gaps that limit its translational applicability. We emphasize the importance of accounting for comorbid conditions, psychosocial impacts, and treatment-specific factors-such as variability among chemotherapeutic agents and adjunct medications. Additionally, we advocate for a multidisciplinary approach to better address dysgeusia in clinical oncology. Our commentary aims to broaden the clinical perspective on dysgeusia and support more comprehensive supportive care strategies.
化疗引起的味觉改变是一种普遍存在但常未被充分认识的并发症，会产生重大的营养和心理社会后果。在这封信中，我们对Köksal等人最近的研究进行了批判性评估，突出了限制其转化应用的关键差距。我们强调考虑合并症、心理社会影响以及特定治疗因素（如化疗药物和辅助药物之间的差异）的重要性。此外，我们主张采用多学科方法，以更好地解决临床肿瘤学中的味觉障碍问题。我们的评论旨在拓宽对味觉障碍的临床视野，并支持更全面的支持性护理策略。
